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Published in 2019 at "ACS chemical biology"
DOI: 10.1021/acschembio.9b00030
Abstract: Rhizocticins are phosphono-oligopeptide antibiotics that contain a toxic C-terminal ( Z) -l -2-amino-5-phosphono-3-pentenoic acid (APPA) moiety. APPA is an irreversible inhibitor of threonine synthase (ThrC), a pyridoxal 5'-phosphate (PLP)-dependent enzyme that catalyzes the conversion of…
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Keywords:
phosphono oligopeptide;
subtilis atcc;
appa;
atcc 6633 ... See more keywords
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Published in 2017 at "Acta Periodica Technologica"
DOI: 10.2298/apt1748245r
Abstract: In the effort to overcome the increase in antimicrobial resistance of different pathogens, natural products from microbial sources appear to be the most favorable alternative to current antibiotics. Production of antimicrobial compounds is highly dependent…
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Keywords:
antimicrobial substances;
production;
subtilis atcc;
atcc 6633 ... See more keywords