Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0218399
Abstract: Aggrecan is an integral component of the extracellular matrix in cartilaginous tissues, including the growth plate. Heterozygous defects in the aggrecan gene have been identified as a cause of autosomal dominant short stature, bone age… read more here.
Keywords: atdc5 cells; chondrocyte differentiation; chondrogenesis; required chondrocyte ... See more keywords
Decalcification of calcified tissues induced by inorganic polyphosphate in chondrogenic ATDC5 cells in the presence of insulin.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of oral science"
DOI: 10.2334/josnusd.24-0429
Abstract: PURPOSE Inorganic polyphosphate (PolyP), a polymer of orthophosphate, strongly promotes mineralized tissue formation. This study explored the conditions necessary for PolyP to induce calcified deposits in cartilage and assessed the role of insulin in modulating… read more here.
Keywords: atdc5; atdc5 cells; insulin; presence insulin ... See more keywords
Hyaluronic Acid Oligosaccharide Derivatives Alleviate Lipopolysaccharide-Induced Inflammation in ATDC5 Cells by Multiple Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27175619
Abstract: High molecular weight hyaluronic acids (HMW-HAs) have been used for the palliative treatment of osteoarthritis (OA) for decades, but the pharmacological activity of HA fragments has not been fully explored due to the limited availability… read more here.
Keywords: atdc5; induced inflammation; acid oligosaccharide; hyaluronic acid ... See more keywords