Effect of Various Ratios of Co‐Cultured ATDC5 Cells and Chondrocytes on the Expression of Cartilaginous Phenotype in Microcavitary Alginate Hydrogel
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DOI: 10.1002/jcb.26218
Abstract: The present study introduced a direct co‐culture of mouse ATDC5 cells and primary porcine chondrocytes into a microcavitary hydrogel, which possessed advantages in promoting the growth of chondrocytes and retaining the phenotype. These two types… read more here.
Keywords: phenotype; cells chondrocytes; effect various; atdc5 cells ... See more keywords
Long noncoding RNA CHRF exacerbates IL‐6‐induced inflammatory damages by downregulating microRNA‐146a in ATDC5 cells
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DOI: 10.1002/jcp.28749
Abstract: Osteoarthritis (OA) is a frequent chronic musculoskeletal disorder which lacks applicably effective therapeutic strategy. In this study, we attempted to investigate whether long noncoding RNA (lncRNA) cardiac hypertrophy‐related factor (CHRF) participated in mediating interleukin‐6 (IL‐6)‐induced… read more here.
Keywords: long noncoding; lncrna chrf; atdc5 cells; noncoding rna ... See more keywords
Long non‐coding RNA activated by transforming growth factor beta alleviates lipopolysaccharide‐induced inflammatory injury via regulating microRNA‐223 in ATDC5 cells
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DOI: 10.1016/j.intimp.2019.01.056
Abstract: &NA; Osteoarthritis (OA) is a conversant joint disease, which seriously threatens the health of the elderly, and even leads to disability. Long non‐coding RNA‐activated by transforming growth factor beta (lncRNA‐ATB) has been reported in diverse… read more here.
Keywords: lncrna atb; inflammatory injury; atdc5 cells; mir 223 ... See more keywords
Kaempferol protects chondrogenic ATDC5 cells against inflammatory injury triggered by lipopolysaccharide through down‐regulating miR‐146a
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.02.014
Abstract: &NA; Kaempferol is a kind of bioflavonoid exerts diverse pharmacological activities, including anti‐apoptotic and anti‐inflammatory activities. Kaempferol has been recognized as an effective agent for alleviating the clinical symptoms of osteoarthritis (OA). This study aimed… read more here.
Keywords: atdc5 cells; kaempferol; mir 146a; inflammatory injury ... See more keywords
Long non-coding RNA highly up-regulated in liver cancer protects tumor necrosis factor-alpha-induced inflammatory injury by down-regulation of microRNA-101 in ATDC5 cells.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.04.004
Abstract: BACKGROUND Osteoarthritis (OA) is a familiar joint degenerative disease. Long non-coding RNAs (lncRNAs) play vital roles in the pathogenesis of OA. Nevertheless, the regulatory impacts of lncRNA highly up-regulated in liver cancer (lncRNA-HULC) on OA… read more here.
Keywords: hulc; mir 101; inflammatory injury; atdc5 cells ... See more keywords
Geniposide promotes the proliferation and differentiation of MC3T3-E1 and ATDC5 cells by regulation of microRNA-214.
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DOI: 10.1016/j.intimp.2019.106121
Abstract: The research plans to make sure how Geniposide (GEN) functions in osteoblast proliferation and differentiation. The MC3T3-E1 and ATDC5 cells were treated with the GEN, XAV-939 and/or transfected with microRNA (miR)-214 mimic or corresponding control.… read more here.
Keywords: mc3t3 atdc5; atdc5 cells; gen; differentiation mc3t3 ... See more keywords
ATDC5 cells as a model of cartilage extracellular matrix neosynthesis, maturation and assembly
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DOI: 10.1016/j.jprot.2020.103718
Abstract: Abstract Fibrillar collagens and proteoglycans (PGs) are quantitatively the major constituents of extracellular matrices (ECM). They carry numerous crucial post-translational modifications (PTMs) that tune the resulting biomechanical properties of the corresponding tissues. The mechanisms determining… read more here.
Keywords: model; atdc5 cells; cells model; cartilage ... See more keywords
Resveratrol Protects Murine Chondrogenic ATDC5 Cells Against LPS-Induced Inflammatory Injury Through Up-Regulating MiR-146b
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DOI: 10.1159/000490141
Abstract: Background/Aims: Resveratrol (RSV) has been reported as a promising oral supplementation for osteoarthritis treatment, while the mechanism of its action is still unclear. The specific aim of this study is to decode one of the… read more here.
Keywords: lps induced; atdc5 cells; rsv; cells lps ... See more keywords
Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells
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DOI: 10.1371/journal.pone.0218399
Abstract: Aggrecan is an integral component of the extracellular matrix in cartilaginous tissues, including the growth plate. Heterozygous defects in the aggrecan gene have been identified as a cause of autosomal dominant short stature, bone age… read more here.
Keywords: atdc5 cells; chondrocyte differentiation; chondrogenesis; required chondrocyte ... See more keywords
Short communication: Milk basic protein promotes proliferation and inhibits differentiation of mouse chondrogenic ATDC5 cells.
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DOI: 10.3168/jds.2018-15656
Abstract: It has been reported that the intake of milk basic protein (MBP) increases bone density by promoting bone formation and suppressing bone resorption. However, few studies have been done on MBP in cartilage, the tissue… read more here.
Keywords: milk basic; atdc5 cells; mbp; differentiation ... See more keywords
In Vitro Screening of Molecularly Engineered Polyethylene Glycol Hydrogels for Cartilage Tissue Engineering using Periosteum-Derived and ATDC5 Cells
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DOI: 10.3390/ijms19113341
Abstract: The rapidly growing field of tissue engineering and regenerative medicine has brought about an increase in demand for biomaterials that mimic closely the form and function of biological tissues. Therefore, understanding the cellular response to… read more here.
Keywords: atdc5 cells; tissue; periosteum derived; polyethylene glycol ... See more keywords