Articles with "atezolizumab plus" as a keyword



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Atezolizumab Plus Bevacizumab as First-line Treatment for Patients With Metastatic Nonsquamous Non–Small Cell Lung Cancer With High Tumor Mutation Burden

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Published in 2022 at "JAMA Oncology"

DOI: 10.1001/jamaoncol.2022.5959

Abstract: This nonrandomized controlled trial evaluates the clinical benefits and safety of atezolizumab plus bevacizumab for treatment of patients with metastatic non–small cell lung cancer (NSCLC) with high tumor mutation burden. read more here.

Keywords: non small; treatment patients; small cell; atezolizumab plus ... See more keywords
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Does first‐line treatment have prognostic impact for unresectable HCC?—Atezolizumab plus bevacizumab versus lenvatinib

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.4854

Abstract: A comparison of therapeutic efficacy between atezolizumab plus bevacizumab (Atez/Bev) and lenvatinib treatment given as first‐line therapy for unresectable hepatocellular carcinoma (u‐HCC) in regard to progression‐free survival (PFS) overall survival (OS) has not been reported.… read more here.

Keywords: prognostic impact; hcc; first line; atezolizumab plus ... See more keywords
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Real‐world data of atezolizumab plus carboplatin and etoposide in elderly patients with extensive‐disease small‐cell lung cancer

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.4938

Abstract: The aim of this study was to assess the effectiveness and tolerability of atezolizumab plus carboplatin and etoposide combination chemotherapy in elderly patients with extensive‐disease (ED) small‐cell lung cancer (SCLC). read more here.

Keywords: elderly patients; carboplatin etoposide; plus carboplatin; patients extensive ... See more keywords
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Results from the IMpower132 China cohort: Atezolizumab plus platinum‐based chemotherapy in advanced non‐small cell lung cancer

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.5144

Abstract: The global Phase III IMpower132 study evaluating atezolizumab plus pemetrexed and carboplatin or cisplatin (APP) versus pemetrexed plus carboplatin or cisplatin (PP) for first‐line treatment of non‐squamous advanced non‐small cell lung cancer (NSCLC) met its… read more here.

Keywords: cancer; non small; small cell; atezolizumab plus ... See more keywords
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Similar efficacy and safety between lenvatinib versus atezolizumab plus bevacizumab as the first‐line treatment for unresectable hepatocellular carcinoma

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.5506

Abstract: Lenvatinib and atezolizumab plus bevacizumab(A + B) have been used for unresectable hepatocellular carcinoma (HCC) as first‐line therapy. Real‐world studies comparison of efficacy and safety in these two regimens are limited, we therefore conduct this study to… read more here.

Keywords: hepatocellular carcinoma; unresectable hepatocellular; first line; atezolizumab plus ... See more keywords
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Preliminary evidence of safety and tolerability of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma and Child-Pugh A and B cirrhosis: a real-world study.

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Published in 2022 at "Hepatology"

DOI: 10.1002/hep.32468

Abstract: BACKGROUND & AIMS Atezolizumab plus bevacizumab (AtezoBev) is the standard of care for first-line treatment of unresectable hepatocellular carcinoma (HCC). No evidence exists as to its use in routine clinical practice in patients with impaired… read more here.

Keywords: atezolizumab plus; hepatocellular carcinoma; child pugh; treatment ... See more keywords
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Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trial

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Published in 2019 at "The Lancet"

DOI: 10.1016/s0140-6736(19)30723-8

Abstract: BACKGROUND A phase 2 trial showed improved progression-free survival for atezolizumab plus bevacizumab versus sunitinib in patients with metastatic renal cell carcinoma who express programmed death-ligand 1 (PD-L1). Here, we report results of IMmotion151, a… read more here.

Keywords: renal cell; cell carcinoma; plus bevacizumab; atezolizumab plus ... See more keywords
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Atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma progressing after molecular targeted therapy: A multicenter prospective observational study

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Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000030871

Abstract: To evaluate the efficacy of atezolizumab plus bevacizumab treatment in patients with hepatocellular carcinoma (HCC) previously treated with molecular targeted agents (MTAs). Thirty-one patients treated with atezolizumab plus bevacizumab for unresectable HCC and previously treated… read more here.

Keywords: bevacizumab treatment; hepatocellular carcinoma; atezolizumab plus; treatment ... See more keywords
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Early response and safety of atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma in patients who do not meet IMbrave150 eligibility criteria

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Published in 2021 at "Hepatology Research"

DOI: 10.1111/hepr.13693

Abstract: A clinical trial (IMbrave150) indicated the efficacy and safety of atezolizumab plus bevacizumab for patients with unresectable hepatocellular carcinoma (HCC). In this study, we evaluated this therapeutic combination in a real‐world setting, with a focus… read more here.

Keywords: hepatocellular carcinoma; unresectable hepatocellular; atezolizumab plus; patients meet ... See more keywords
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Therapeutic efficacy of atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma in patients with Child‐Pugh class A or B liver function in real‐world clinical practice

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Published in 2022 at "Hepatology Research"

DOI: 10.1111/hepr.13797

Abstract: Atezolizumab plus bevacizumab (Atez/Bev) treatment is recommended for unresechepatocellular carcinoma (u‐HCC) patients classified as Child‐Pugh A (CP‐A). This study aimed to elucidate the prognosis of patients treated with Atez/Bev, especially CP‐A and ‐B cases. read more here.

Keywords: plus bevacizumab; child pugh; atezolizumab plus; treatment ... See more keywords
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Significance of ramucirumab following atezolizumab plus bevacizumab therapy for hepatocellular carcinoma using real‐world data

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Published in 2022 at "Hepatology Research"

DOI: 10.1111/hepr.13852

Abstract: Few studies have reported the efficacy and safety of ramucirumab (RAM) after atezolizumab plus bevacizumab (Atezo/Beva) treatment and the overall associated outcomes. Thus, we aimed to evaluate the therapeutic effects and safety of RAM post‐treatment… read more here.

Keywords: ramucirumab following; atezolizumab plus; following atezolizumab; significance ramucirumab ... See more keywords