Targeted Deletion of ATF4 in ß Cells Leads to the Vulnerability and Dedifferentiation during ER Stress
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DOI: 10.2337/db18-2104-p
Abstract: ATF4 is the main transcriptional regulator of the Unfolded Protein Response (UPR) that promote restoration of normal ER function, although the contribution of ATF4 on β-cells remains poorly understood. Therefore, we developed mature β-cell specific… read more here.
Keywords: atf4; atf4 cells; stress; none ... See more keywords