Oridonin ameliorates acetaminophen‐induced acute liver injury through ATF4/PGC‐1α pathway
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DOI: 10.1002/ddr.22024
Abstract: Acetaminophen (APAP) overdose‐induced acute liver injury (ALI) causes hepatocyte cell death, oxidative stress, and inflammation. Oridonin (Ori), a covalent NLRP3‐inflammasome inhibitor, ameliorates APAP‐induced ALI through an unclear molecular mechanism. This study found that Ori decreased… read more here.
Keywords: apap; atf4 pgc; liver injury; acute liver ... See more keywords