A facile forward-genetic screen for Arabidopsis autophagy mutants reveals twenty-one loss-of-function mutations disrupting six ATG genes
Sign Up to like & getrecommendations! Published in 2019 at "Autophagy"
DOI: 10.1080/15548627.2019.1569915
Abstract: ABSTRACT Macroautophagy is a process through which eukaryotic cells degrade large substrates including organelles, protein aggregates, and invading pathogens. Over 40 autophagy-related (ATG) genes have been identified through forward-genetic screens in yeast. Although homology-based analyses… read more here.
Keywords: screen; autophagy; facile forward; arabidopsis ... See more keywords
Independent losses and duplications of autophagy‐related genes in fungal tree of life
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Microbiology"
DOI: 10.1111/1462-2920.14451
Abstract: Autophagy is important for growth, development and pathogenesis in fungi. Although autophagic process is generally considered to be conserved, the conservation and evolution of ATG genes at kingdom-wide remains to be conducted. Here we systematically… read more here.
Keywords: losses duplications; independent losses; autophagy related; atg genes ... See more keywords
ATG Genes Influence the Virulence of Cryptococcus neoformans through Contributions beyond Core Autophagy Functions
Sign Up to like & getrecommendations! Published in 2018 at "Infection and Immunity"
DOI: 10.1128/iai.00069-18
Abstract: The process of autophagy is conserved among all eukaryotes from yeast to humans and is mainly responsible for bulk degradation of cellular contents and nutrient recycling during starvation. Autophagy has been suggested to play a… read more here.
Keywords: cryptococcus neoformans; beyond core; virulence; autophagy ... See more keywords
Marchantia polymorpha, a New Model Plant for Autophagy Studies
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2019.00935
Abstract: Autophagy is a catabolic process for bulk and selective degradation of cytoplasmic components in the vacuole/lysosome. In Saccharomyces cerevisiae, ATG genes were identified as essential genes for autophagy, and most ATG genes are highly conserved… read more here.
Keywords: marchantia polymorpha; model; plant; atg genes ... See more keywords
The expression characteristics and prognostic roles of autophagy-related genes in gastric cancer
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.10814
Abstract: Background Autophagy is an evolutionally highly conserved process, accompanied by the dynamic changes of various molecules, which is necessary for the orderly degradation and recycling of cellular components. The aim of the study was to… read more here.
Keywords: gastric cancer; expression; related genes; autophagy related ... See more keywords