Recruitment and Activation of the ULK1/Atg1 Kinase Complex in Selective Autophagy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Biology"
DOI: 10.1016/j.jmb.2019.07.027
Abstract: Autophagy is a major cellular degradation pathway, which mediates the delivery of cytoplasmic cargo material into lysosomes. This is achieved by the specific sequestration of the cargo within double-membrane vesicles, the autophagosomes, which form de… read more here.
Keywords: ulk1 atg1; selective autophagy; kinase complex; atg1 kinase ... See more keywords
Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.10.024
Abstract: Autophagy is a conserved intracellular degradation pathway exerting various cytoprotective and homeostatic functions by using de novo double-membrane vesicle (autophagosome) formation to target a wide range of cytoplasmic material for vacuolar/lysosomal degradation. The Atg1 kinase… read more here.
Keywords: formation; regulation autophagy; atg1 kinase; autophagosome formation ... See more keywords