Experimental diabetes exacerbates autophagic flux impairment during myocardial I/R injury through calpain‐mediated cleavage of Atg5/LAMP2
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DOI: 10.1111/jcmm.17642
Abstract: To explore the role of autophagic flux in the increased susceptibility of the experimental diabetic heart to ischaemia‐reperfusion (I/R) injury, we established STZ‐induced diabetic mice and performed I/R. In vitro, neonatal mouse cardiomyocytes were subjected… read more here.
Keywords: atg5 lamp2; autophagic flux; experimental diabetes; flux impairment ... See more keywords