284-OR: Physiologic Compensation to Metabolic Stress following Islet α-Cell Loss
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DOI: 10.2337/db25-284-or
Abstract: Introduction and Objective: Islet endocrine cells rely on efficient prohormone synthesis and elimination of misfolded peptides for proper function. We recently found that endoplasmic reticulum-associated degradation (ERAD) and autophagy are essential protein quality control systems… read more here.
Keywords: atg7 gcg; gcg; cell; islet ... See more keywords