Structure-Function Relationship for a Divergent Atg8 Protein Required for a Nonautophagic Function in Apicomplexan Parasites
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DOI: 10.1128/mbio.03642-21
Abstract: The most extensively studied role of Atg8 proteins is in autophagy. However, it is clear that they have other nonautophagic functions critical to cell function and disease pathogenesis that are so far understudied compared to… read more here.
Keywords: function; atg8 protein; atg8; role ... See more keywords
A unifying model for the role of the ATG8 system in autophagy.
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DOI: 10.1242/jcs.258997
Abstract: The formation of autophagosomes and their fusion with lysosomes are key events that underpin autophagic degradation of cargoes. The core ATG8 system, which consists of the ATG8 family of ubiquitin-like proteins and the machineries that… read more here.
Keywords: atg8; atg8 system; unifying model; core atg8 ... See more keywords
Proteomic analysis of Atg8-dependent recruitment of phagosomal proteins in the enteric protozoan parasite Entamoeba histolytica
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DOI: 10.3389/fcimb.2022.961645
Abstract: Autophagy is one of the bulk degradation systems and is conserved throughout eukaryotes. In the enteric protozoan parasite Entamoeba histolytica, the causative agent of human amebiasis, Atg8 is not exclusively involved in autophagy per se… read more here.
Keywords: atg8 dependent; histolytica; atg8; parasite entamoeba ... See more keywords