The interplay between pathogens and Atg8 family proteins: thousand-faced interactions.
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DOI: 10.1002/2211-5463.13318
Abstract: Autophagy is an intracellular degradation and recycling process that can also remove pathogenic intracellular bacteria and viruses from within cells (referred to as xenophagy) and activate the adaptive immune responses. But autophagy - especially Atg… read more here.
Keywords: atg8 family; interplay pathogens; family; pathogens atg8 ... See more keywords
A new flavor of cellular Atg8-family protein lipidation – alternative conjugation to phosphatidylserine during CASM
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DOI: 10.1080/15548627.2021.1947730
Abstract: ABSTRACT Atg8-family protein lipidation is the most commonly used marker for monitoring autophagy. During macroautophagy, Atg8-family proteins are specifically conjugated to phosphatidylethanolamine (PE) in forming, double-membrane autophagosomes. A distinct, non-canonical autophagy pathway also operates, characterized… read more here.
Keywords: atg8 family; protein lipidation; family protein; family ... See more keywords
Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
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DOI: 10.1080/15548627.2022.2039535
Abstract: ABSTRACT Chloroquine (CQ), a lysosomotropic agent, is commonly used to inhibit lysosomal degradation and macroautophagy/autophagy. Here we investigated the cell-extrinsic effects of CQ on secretion. We showed that lysosomal and autophagy inhibition by CQ altered… read more here.
Keywords: family; atg8 family; family proteins; autophagy related ... See more keywords