Atg8–PE protein-based in vitro biochemical approaches to autophagy studies
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2025572
Abstract: ABSTRACT Macroautophagy/autophagy is an evolutionarily conserved intracellular degradation pathway that maintains cellular homeostasis. Over the past two decades, a series of scientific breakthroughs have helped explain autophagy-related molecular mechanisms and physiological functions. This tremendous progress… read more here.
Keywords: autophagy studies; atg8 protein; based vitro; protein based ... See more keywords
Structure-Function Relationship for a Divergent Atg8 Protein Required for a Nonautophagic Function in Apicomplexan Parasites
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DOI: 10.1128/mbio.03642-21
Abstract: The most extensively studied role of Atg8 proteins is in autophagy. However, it is clear that they have other nonautophagic functions critical to cell function and disease pathogenesis that are so far understudied compared to… read more here.
Keywords: function; atg8 protein; atg8; role ... See more keywords
AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research
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DOI: 10.1371/journal.pbio.3002002
Abstract: In this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence–based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy. read more here.
Keywords: protein binding; atg8 protein; predicts atg8; alphafold multimer ... See more keywords