Inhibition of mitochondrial activity ameliorates atherosclerosis in ApoE−/− mice via suppressing vascular smooth cell activation and macrophage foam cell formation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29042
Abstract: Atherosclerosis involves disorders in lipoprotein metabolism and inflammation. Mitochondrial dysfunction plays a critical role in promoting cell apoptosis, inflammation, and oxidative stress involved in the progress of atherosclerosis. Whereas the direct effect of mitochondrial activity… read more here.
Keywords: atherosclerosis apoe; mice; mitochondrial activity; cell ... See more keywords
Food with calorie restriction reduces the development of atherosclerosis in apoE-deficient mice.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.01.109
Abstract: Calorie restriction (CR) ameliorates various diseases including cardiovascular disease. However, its protection and underlying mechanisms against atherosclerosis remain un-fully elucidated. In this study, we fed apoE deficient (apoE-/-) mice in Control group a high-fat diet… read more here.
Keywords: calorie restriction; atherosclerosis apoe; mice; apoe deficient ... See more keywords