Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE−/− mice
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DOI: 10.1371/journal.pone.0282685
Abstract: Chronic low-grade inflammation is regarded to an important signature of atherosclerosis (AS). Macrophage (Mψ) and related polarization have been demonstrated to play a crucial role in the occurrence and development of AS inflammation. Butyrate, a… read more here.
Keywords: inflammation; atherosclerotic inflammation; inflammation regulating; butyrate ... See more keywords
Plasma APE1/Ref-1 Correlates with Atherosclerotic Inflammation in ApoE−/− Mice
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DOI: 10.3390/biomedicines8090366
Abstract: Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is involved in DNA base repair and reducing activity. However, the role of APE1/Ref-1 in atherosclerosis is unclear. Herein, we investigated the role of APE1/Ref-1 in atherosclerotic apolipoprotein E (ApoE−/−)… read more here.
Keywords: ape1 ref; atherosclerotic inflammation; ref; apoe mice ... See more keywords