Lipocalin-2 contributes to experimental atherosclerosis in a stage-dependent manner.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.06.015
Abstract: BACKGROUND AND AIMS Lipocalin-2 (Lcn2) is a glycoprotein which can be secreted by immune cells. Several studies in humans have suggested Lcn2 can be used as a biomarker for the detection of unstable atherosclerotic lesions,… read more here.
Keywords: lipocalin contributes; ldlr lcn2; atherosclerotic lesions; lcn2 mice ... See more keywords
The different relations of PCSK9 and Lp(a) to the presence and severity of atherosclerotic lesions in patients with familial hypercholesterolemia.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.07.030
Abstract: BACKGROUND AND AIMS The relation of lipoprotein (a) [Lp(a)] and proprotein convertase substilisin/kexin type 9 (PCSK9) levels to coronary artery disease (CAD) has been well established in the general population, while little is known about… read more here.
Keywords: presence severity; patients familial; pcsk9 presence; severity ... See more keywords
Gpihbp1 deficiency accelerates atherosclerosis and plaque instability in diabetic Ldlr-/- mice.
Sign Up to like & getrecommendations! Published in 2019 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2019.01.025
Abstract: BACKGROUND AND AIMS Glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 (GPIHBP1) plays a crucial role in triglyceride hydrolysis, and GPIHBP1 deficiency leads to severe hypertriglyceridemia (HTG). Gpihbp1 knockout (GKO) mice develop mild lesions in the aortic… read more here.
Keywords: gpihbp1 deficiency; atherosclerotic lesions; mice; deficiency accelerates ... See more keywords
The intima with early atherosclerotic lesions is load-bearing component of human thoracic aorta
Sign Up to like & getrecommendations! Published in 2017 at "Biocybernetics and Biomedical Engineering"
DOI: 10.1016/j.bbe.2016.10.008
Abstract: Abstract The aim of the study was to evaluate the mechanical properties of the adventitia, media, and especially intima of the human thoracic aortic wall in the early stages of atherosclerosis (stage I to III… read more here.
Keywords: human thoracic; intima early; atherosclerotic lesions; kpa ... See more keywords
Activation of NLRP3 inflammasome by cholesterol crystals in alcohol consumption induces atherosclerotic lesions
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.02.014
Abstract: Epidemiological studies showed a strong association between alcoholism and incidence of stroke, for which the underlying causative mechanisms remain to be understood. Here we found that infiltration of immune cells and deposition of cholesterol at… read more here.
Keywords: cholesterol; activation nlrp3; atherosclerotic lesions; activation ... See more keywords
Long-term administration of low-dose selenium nanoparticles with different sizes aggravated atherosclerotic lesions and exhibited toxicity in apolipoprotein E-deficient mice.
Sign Up to like & getrecommendations! Published in 2021 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2021.109601
Abstract: Exploration of long-term in vivo effects of nanomaterials, particularly those with potential biomedical applications, is quite important for better understanding and evaluating their biosafety. Selenium nanoparticles (SeNPs) has been considered as a good candidate in… read more here.
Keywords: aggravated atherosclerotic; administration; low dose; term ... See more keywords
IL-33/IL-33R in various types of carotid artery atherosclerotic lesions.
Sign Up to like & getrecommendations! Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2019.05.010
Abstract: OBJECTIVE Inflammation plays a crucial role in the progression of atherosclerotic plaques. The aim of the study was to investigate serum levels and expression of Interleukin-33 (IL-33) and ST2 receptor in atherosclerotic plaques and to… read more here.
Keywords: atherosclerotic plaques; carotid artery; expression; atherosclerotic lesions ... See more keywords
Establishment of type 2 diabetes mellitus models using streptozotocin after 3 months high-fat diet in Bama minipigs.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2088548
Abstract: In the past twenty years, the number of adults with diabetes has tripled. Most studies have been conducted using rodent models of type 2 diabetes mellitus (T2DM), and the developed drugs have low clinical conversion… read more here.
Keywords: stz; atherosclerotic lesions; hcfd; high fat ... See more keywords
Noninvasive detection of matrix metalloproteinase-9 in atherosclerotic lesions using technetium-99m-labeled single-photon emission computed tomography in vivo
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DOI: 10.1097/mnm.0000000000000651
Abstract: Objective Previous studies have suggested that matrix metalloproteinase (MMP) inhibitor uptake may offer a precise estimation of MMP activity in atherosclerotic lesions. In this study, we explored the feasibility of noninvasive detection of MMP-9 activity… read more here.
Keywords: vivo; matrix metalloproteinase; atherosclerotic lesions; using technetium ... See more keywords
Moxibustion at CV4 alleviates atherosclerotic lesions through activation of the LXRα/ABCA1 pathway in apolipoprotein-E-deficient mice
Sign Up to like & getrecommendations! Published in 2019 at "Acupuncture in Medicine"
DOI: 10.1136/acupmed-2016-011317
Abstract: Objectives: To investigate the anti-atherogenic effect of moxibustion and whether it is mediated through the reverse cholesterol transport process. Methods: 8-week-old male apolipoprotein E deficient (ApoE−/− knockout) mice were randomly divided into two groups (n=10… read more here.
Keywords: moxibustion; thoracic aorta; lxr abca1; atherosclerotic lesions ... See more keywords
THU0502 Assessment of severity of atherosclerotic lesions of carotid arteries in men with coronary heart disease depending on bone mineral density and risk of osteoporotic fractures
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.5548
Abstract: Objectives To assess severity of atherosclerotic lesions of carotid arteries (CA) in men with coronary heart disease (CHD) depending on bone mineral density (BMD) and risk of osteoporotic fractures according to FRAX scale. Methods The… read more here.
Keywords: risk; criterion; severity atherosclerotic; atherosclerotic lesions ... See more keywords