Low‐Intensity Focused Ultrasound‐Responsive Ferrite‐Encapsulated Nanoparticles for Atherosclerotic Plaque Neovascularization Theranostics
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202100850
Abstract: Abstract Pathological angiogenesis is a crucial factor that causes atherosclerotic plaque rupture. Sinoporphyrin sodium‐mediated sonodynamic therapy (DVDMS‐SDT) induces regression of plaque neovascularization in humans without causing obvious side effects. However, a clinical noninvasive theranostic strategy… read more here.
Keywords: phpmr mediated; mediated sdt; plaque neovascularization; plaque ... See more keywords
A Carotid Web with Atherosclerotic Plaque
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26508
Abstract: 2 infarc-tion the carotid with a carotid (CaW), a at atherosclerotic plaque under it a membranous the the lumen read more here.
Keywords: atherosclerotic plaque; carotid web; carotid; web atherosclerotic ... See more keywords
Analysis of atherosclerotic plaque distribution in the carotid artery
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cardiology"
DOI: 10.1002/clc.23903
Abstract: The present study was designed to investigate the hypothesis that the outer wall at the carotid bifurcation is the most common area of atherosclerotic plaque deposition due to the low shear stress. read more here.
Keywords: atherosclerotic plaque; plaque distribution; carotid; analysis atherosclerotic ... See more keywords
Absence of the Vitamin D Receptor Inhibits Atherosclerotic Plaque Calcification in Female Hypercholesterolemic Mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25679
Abstract: Epidemiological and clinical data suggest adverse cardiovascular outcomes with respect to vitamin D deficiency. Here, we explored the effects of vitamin D in atherosclerotic plaque calcification in vivo by utilizing vitamin D receptor (Vdr)‐deficient mice… read more here.
Keywords: vdr; calcification; mice; plaque calcification ... See more keywords
Mechanical characterization of 3D printed mimic of human artery affected by atherosclerotic plaque through numerical and experimental methods.
Sign Up to like & getrecommendations! Published in 2021 at "Biomechanics and modeling in mechanobiology"
DOI: 10.1007/s10237-021-01487-9
Abstract: This paper proposes a novel experimental investigation based on 3D printing to validate numerical models for biomechanics simulations. Soft elastomeric materials have been used in Polyjet multi-material 3D printer to mimicking arteries affected by atherosclerotic… read more here.
Keywords: artery; affected atherosclerotic; biomechanics; mechanical characterization ... See more keywords
Coupled Modeling of Lipid Deposition, Inflammatory Response and Intraplaque Angiogenesis in Atherosclerotic Plaque
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-018-02173-1
Abstract: We propose a multiphysical mathematical model by fully coupling lipid deposition, monocytes/macrophages recruitment and angiogenesis to investigate the pathophysiological responses of an atherosclerotic plaque to the dynamic changes in the microenvironment. The time evolutions of… read more here.
Keywords: lipid deposition; inflammatory; angiogenesis; atherosclerotic plaque ... See more keywords
Atherosclerotic plaque metabolism in high cardiovascular risk subjects - A subclinical atherosclerosis imaging study with 18F-NaF PET-CT.
Sign Up to like & getrecommendations! Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.03.014
Abstract: BACKGROUND AND AIMS Atherosclerotic plaque molecular imaging with 18F-sodium fluoride (NaF) in positron emission tomography with computed tomography (PET-CT) provides potential discrimination between active unstable microcalcification and established dormant calcification. We aimed to study 18F-NaF… read more here.
Keywords: study 18f; risk; 18f naf; high cardiovascular ... See more keywords
IL-7R blockade reduces post-myocardial infarction-induced atherosclerotic plaque inflammation in ApoE−/- mice
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2019.100647
Abstract: Modulating inflammation by targeting IL-1β reduces recurrent athero-thrombotic cardiovascular events without lipid lowering. This presents an opportunity to explore other pathways associated with the IL-1β signaling cascade to modulate the inflammatory response post-myocardial infarction (MI).… read more here.
Keywords: plaque inflammation; inflammation; post myocardial; mice ... See more keywords
Capacitance imaging for the discrimination of lipid region in atherosclerotic plaque ex vivo using polypyrrole-coated multi-walled carbon nanotube multi-electrode array
Sign Up to like & getrecommendations! Published in 2019 at "Current Applied Physics"
DOI: 10.1016/j.cap.2019.08.006
Abstract: Abstract We have developed a capacitance imaging technique using polypyrrole (PPy)-coated multi walled carbon nanotube multi electrode array (PPy-MWCNT-MEA) for the discrimination of lipid region in atherosclerotic plaque ex vivo. The lipid region in the… read more here.
Keywords: capacitance imaging; atherosclerotic plaque; lipid region; multi ... See more keywords
Numerical investigation of atherosclerotic plaque rupture using optical coherence tomography imaging and XFEM
Sign Up to like & getrecommendations! Published in 2018 at "Engineering Fracture Mechanics"
DOI: 10.1016/j.engfracmech.2018.11.002
Abstract: Myocardial infarction contributes to most fatalities in which atherosclerotic plaque disruption is the underlying pathology. From the mechanics view point, the pulsatile blood flow in the arteries resembles a fatigue environment and generates stresses that… read more here.
Keywords: optical coherence; rupture; xfem; coherence tomography ... See more keywords
Oxidized lipids in atherosclerotic plaque instability
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.05.021
Abstract: A large body of evidence suggests a mechanistic link between oxidized lipids and atherosclerosis. Oxysterols and 4-hydroxynonenal (HNE), the major products deriving from LDL oxidation, are consistently present in inflamed and atherosclerotic arteries and they… read more here.
Keywords: oxidized lipids; plaque; oxysterols hne; plaque instability ... See more keywords