ErbB4 alternative splicing mediates fetal mouse alveolar type II cell differentiation in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Research"
DOI: 10.1038/s41390-022-02013-y
Abstract: Alternative splicing (AS) creates different protein isoforms, an important mechanism regulating cell-specific function. Little is known about AS in lung development, particularly in alveolar type II (ATII) cells. ErbB4 receptor isoforms Jma and Jmb have… read more here.
Keywords: differentiation; atii cells; erbb4; cell ... See more keywords
Hypocapnia, mitochondria and surfactant secretion
Sign Up to like & getrecommendations! Published in 2019 at "Thorax"
DOI: 10.1136/thoraxjnl-2018-212624
Abstract: Surfactant, a phospholipoprotein produced and stored by alveolar type II (ATII) cells, lowers surface tension in the alveolus and distal airways and is essential for normal lung mechanics and gas exchange.1 Decreases in surfactant production… read more here.
Keywords: hypocapnia mitochondria; atii cells; hypocapnia; surfactant secretion ... See more keywords
Preventable ATII Proliferation after Hyperoxia: The “Tempo” of Folate Metabolism in the Neonatal Lung
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2022-0012ed
Abstract: Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs at high rates in survivors of premature birth (1). BPD was originally described in 1967 by Northway and colleagues as an airway and parenchymal lung… read more here.
Keywords: atii proliferation; hyperoxia; proliferation; lung ... See more keywords
Transcriptome and Metabolome Integration Provides New Insights Into the Regulatory Networks of Tibetan Pig Alveolar Type II Epithelial Cells in Response to Hypoxia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.812411
Abstract: Tibetan pigs show a widespread distribution in plateau environments and exhibit striking physiological and phenotypic differences from others pigs for adaptation to hypoxic conditions. However, the regulation of mRNAs and metabolites as well as their… read more here.
Keywords: cells tibetan; tibetan pigs; alveolar type; landrace pigs ... See more keywords
Characterization of circRNA–miRNA–mRNA networks regulating oxygen utilization in type II alveolar epithelial cells of Tibetan pigs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.854250
Abstract: Understanding the signaling pathway regulatory mechanisms in type II alveolar epithelial (ATII) cells, the progenitor cells responsible for proliferating and regenerating type I alveolar epithelial (ATI) and ATII cells, in Tibetan pigs is beneficial for… read more here.
Keywords: cells tibetan; tibetan pigs; alveolar epithelial; atii cells ... See more keywords
Alternative splicing signature of alveolar type II epithelial cells of Tibetan pigs under hypoxia-induced
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.984703
Abstract: Alternative splicing (AS) allows the generation of multiple transcript variants from a single gene and affects biological processes by generating protein diversity in organisms. In total, 41,642 AS events corresponding to 9,924 genes were identified,… read more here.
Keywords: type epithelial; alternatively spliced; alternative splicing; alveolar type ... See more keywords
Mitochondrial Ribosome Dysfunction in Human Alveolar Type II Cells in Emphysema
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DOI: 10.3390/biomedicines10071497
Abstract: Pulmonary emphysema is characterized by airspace enlargement and the destruction of alveoli. Alveolar type II (ATII) cells are very abundant in mitochondria. OXPHOS complexes are composed of proteins encoded by the mitochondrial and nuclear genomes.… read more here.
Keywords: alveolar type; dysfunction; atii cells; cells emphysema ... See more keywords
microRNA Expression Profile of Purified Alveolar Epithelial Type II Cells
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13081420
Abstract: Alveolar type II (ATII) cells are essential for the maintenance of the alveolar homeostasis. However, knowledge of the expression of the miRNAs and miRNA-regulated networks which control homeostasis and coordinate diverse functions of murine ATII… read more here.
Keywords: profile purified; expression profile; microrna expression; type ... See more keywords