Atractylodin targets GLA to regulate D‐mannose metabolism to inhibit osteogenic differentiation of human valve interstitial cells and ameliorate aortic valve calcification
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7628
Abstract: Atractylodin (ATL) has been reported to exert anti‐inflammatory effects. Osteogenic changes induced by inflammation in valve interstitial cells (VICs) play a key role in the development of calcified aortic valve disease (CAVD). This study aimed… read more here.
Keywords: aortic valve; calcification; atl; valve calcification ... See more keywords
High expression of NAMPT in adult T-cell leukemia/lymphoma and anti-tumor activity of a NAMPT inhibitor.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172738
Abstract: Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature T lymphocytes induced by human T-cell leukemia virus-1 and has a poor outcome. New molecular targets for the prevention and treatment of ATL are needed urgently.… read more here.
Keywords: cell leukemia; atl; expression; cell ... See more keywords
Terephthalic acid-based magnetic molecularly imprinted polymer for enantioselective capillary electrophoresis determination of atenolol in human plasma
Sign Up to like & getrecommendations! Published in 2021 at "Separation and Purification Technology"
DOI: 10.1016/j.seppur.2020.118257
Abstract: Abstract A new magnetic molecularly imprinted polymer (MMIP) was firstly synthesized using terephthalic acid as a functional monomer to extract atenolol (ATL) from human plasma by magnetic solid phase extraction (MSPE). ATL enantiomers separation was… read more here.
Keywords: magnetic molecularly; plasma; human plasma; atl ... See more keywords
Prognostic impact of organ involvement in aggressive adult T-cell leukemia/lymphoma: definition of risk organ and proposal of a prognostic index
Sign Up to like & getrecommendations! Published in 2025 at "Blood Cancer Journal"
DOI: 10.1038/s41408-025-01367-w
Abstract: To the Editor: Adult T-cell leukemia/lymphoma (ATL) is a lymphoma with a very poor prognosis, originating from the tumorigenesis of human T-cell leukemia virus (HTLV)-1-infected T lymphocytes [1, 2]. The acute, lymphoma, and chronic types… read more here.
Keywords: aggressive atl; stage; cell leukemia; lymphoma ... See more keywords
Modulation of proper name recall by transcranial direct current stimulation of the anterior temporal lobes
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-09781-x
Abstract: We often fail to recall another person's name. Proper names might be more difficult to memorize and retrieve than other pieces of knowledge, such as one's profession because they are processed differently in the brain.… read more here.
Keywords: person; anterior temporal; atl; name ... See more keywords
A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients
Sign Up to like & getrecommendations! Published in 2018 at "Oncoimmunology"
DOI: 10.1080/2162402x.2018.1426423
Abstract: ABSTRACT Adult T-cell leukemia (ATL) is an aggressive, chemotherapy-resistant CD4+CD25+ leukemia caused by HTLV-1 infection, which usually develops in a minority of patients several decades after infection. IFN + AZT combination therapy has shown clinical… read more here.
Keywords: fas; apoptosis; ifn; tscm ... See more keywords
High NAMPT expression and anti-tumour activity of NAMPT inhibitor in adult T-cell leukemia/lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz244.067
Abstract: Abstract Background Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature T lymphocytes induced by human T-cell leukemia virus-1, and has a poor outcome. New molecular targets for the prevention and treatment of ATL are… read more here.
Keywords: inhibitor; cell leukemia; adult cell; atl ... See more keywords
Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T‐cell leukemia
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Science"
DOI: 10.1111/cas.13431
Abstract: Adult T‐cell leukemia (ATL) has a poor prognosis as a result of severe immunosuppression and rapid tumor progression with resistance to conventional chemotherapy. Recent integrated‐genome analysis has revealed mutations in many genes involved in the… read more here.
Keywords: cell leukemia; target; mtorc1; atl ... See more keywords
Alvocidib inhibits IRF4 expression via super‐enhancer suppression and adult T‐cell leukemia/lymphoma cell growth
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15550
Abstract: Adult T‐cell leukemia/lymphoma (ATL) is an intractable hematological malignancy with extremely poor prognosis. Recent studies have revealed that super‐enhancers (SE) play important roles in controlling tumor‐specific gene expression and are potential therapeutic targets for neoplastic… read more here.
Keywords: cell; atl; leukemia lymphoma; adult cell ... See more keywords
The Major Autolysin Atl Regulates the Virulence of Staphylococcus aureus by Controlling the Sorting of LukAB
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00056-22
Abstract: Infections caused by the Gram-positive bacterium Staphylococcus aureus remain a significant health threat globally. The production of bicomponent pore-forming leukocidins plays an important role in S. aureus pathogenesis. ABSTRACT Infections caused by the Gram-positive bacterium… read more here.
Keywords: atl; sorting lukab; staphylococcus aureus; autolysin atl ... See more keywords
Long Noncoding RNA ANRIL Supports Proliferation of Adult T-Cell Leukemia Cells through Cooperation with EZH2
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.00909-18
Abstract: Human T-cell leukemia virus type 1 (HTLV-1) is the pathogen that causes adult T-cell leukemia (ATL), which is a unique malignancy of CD4+ T cells. A role for long noncoding RNA (lncRNA) in HTLV-1-mediated cellular… read more here.
Keywords: htlv; cell leukemia; proliferation; atl ... See more keywords