Articles with "atlas aging" as a keyword



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An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics

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Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-08831-9

Abstract: Aging promotes lung function decline and susceptibility to chronic lung diseases, which are the third leading cause of death worldwide. Here, we use single cell transcriptomics and mass spectrometry-based proteomics to quantify changes in cellular… read more here.

Keywords: single cell; cell transcriptomics; aging lung; atlas aging ... See more keywords
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A metabolome atlas of the aging mouse brain.

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Published in 2021 at "Nature communications"

DOI: 10.1038/s41467-021-26310-y

Abstract: The mammalian brain relies on neurochemistry to fulfill its functions. Yet, the complexity of the brain metabolome and its changes during diseases or aging remain poorly understood. Here, we generate a metabolome atlas of the… read more here.

Keywords: mouse brain; atlas aging; brain metabolome; brain ... See more keywords