Articles with "atoh1 gfi1" as a keyword



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Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-78167-8

Abstract: Mature mammalian cochlear hair cells (HCs) do not spontaneously regenerate once lost, leading to life-long hearing deficits. Attempts to induce HC regeneration in adult mammals have used over-expression of the HC-specific transcription factor Atoh1, but… read more here.

Keywords: adult; regeneration; gfi1; expression ... See more keywords