Dichotomy of Atom-Economical Hydrogen-Free Reductive Amidation vs Exhaustive Reductive Amination.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02821
Abstract: Rh-catalyzed one-step reductive amidation of aldehydes has been developed. The protocol does not require an external hydrogen source and employs carbon monoxide as a deoxygenative agent. The direction of the reaction can be altered simply… read more here.
Keywords: dichotomy atom; economical hydrogen; atom economical; amidation ... See more keywords
An atom-economical protocol for direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes in water
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DOI: 10.1039/c7gc01483j
Abstract: This paper describes an atom-economical strategy for the direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes under metal free conditions with excellent functional group tolerance. The use of stable-nontoxic Oxone as a terminal oxidant along… read more here.
Keywords: hillman alcohols; baylis hillman; chemistry; conversion baylis ... See more keywords
Atom Economical Multi-Substituted Pyrrole Synthesis from Aziridine
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DOI: 10.3390/molecules27206869
Abstract: Multi-substituted pyrroles are synthesized from regiospecific aziridine ring-opening and subsequent intramolecular cyclization with a carbonyl group at the γ-position in the presence of Lewis acid or protic acid. This method is highly atom economical where… read more here.
Keywords: economical multi; synthesis; atom economical; aziridine ... See more keywords