Single‐Atom Nanozymes for Catalytic Therapy: Recent Advances and Challenges
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202312116
Abstract: As a powerful tool, nanozyme catalysts broaden the avenues to implement bio‐inspired solutions for addressing many important concerns, covering energy, healthcare, the environment, and more. Recent endeavors, characterized by atomic precision, have enabled extensive exploration… read more here.
Keywords: nanozymes catalytic; therapy; catalytic therapy; atom nanozymes ... See more keywords
Advanced Enzyme Mimicking Engineering: 3D Biomimetic Pt Single‐Atom Nanozymes Initiating Pressure‐Driven Device
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202402552
Abstract: Current research on single‐atom nanozymes has predominantly concentrated on 2D structures, with limited exploration into the influence of 3D biomimetic structures on their catalytic performance. In this work, a 3D nanostructure of Pt single‐atom nanozyme… read more here.
Keywords: pressure; enzyme mimicking; atom; atom nanozymes ... See more keywords
Spatially Axial Boron Coordinated Single‐Atom Nanozymes with Boosted Multi‐Enzymatic Performances for Periodontitis Treatment
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202403386
Abstract: Single‐atom nanozymes (SAzymes) have made significant strides in antibacterial treatment but fall short as natural enzyme and drug replacements due to limited catalytic performance. Here, a rational strategy is presented for incorporating spatially axial boron… read more here.
Keywords: treatment; axial boron; atom nanozymes; spatially axial ... See more keywords
Multi‐Hierarchical Fe Single Atom Nanozymes with Axially‐Coordinated O‐Fe‐N4 Active Centers Reshape Macrophage Epigenetics Against Immunosuppression
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202408141
Abstract: Immunosuppression is ubiquitous in solid tumors, characterized by few cytotoxic T infiltrations, abundant inflammation enrichment, immunosuppressive cell recruitment, etc., which is especially potentiated by incomplete tumor resection. In this report, multi‐hierarchical Fe single‐atom nanozymes (SAzymes)… read more here.
Keywords: atom nanozymes; hierarchical single; active centers; immunosuppression ... See more keywords
Dual‐Atom Nanozymes (DAzymes): from Synthesis to Applications
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202506110
Abstract: Dual‐atom nanozymes (DAzymes), a novel category of nanozyme characterized by paired metal atoms serving as catalytic centers, have attracted considerable interest. DAzyme pursuit due to the exceptional catalytic performance, improved stability, and adaptable specificity compared… read more here.
Keywords: dazymes synthesis; dual atom; atom nanozymes; metal ... See more keywords
Engineering Single-Atom Nanozymes for Catalytic Biomedical Applications.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202300750
Abstract: Nanomaterials with enzyme-mimicking properties, coined as nanozymes, are a promising alternative to natural enzymes owing to their remarkable advantages, such as high stability, easy preparation, and favorable catalytic performance. Recently, with the rapid development of… read more here.
Keywords: nanozymes catalytic; single atom; biomedical applications; atom nanozymes ... See more keywords
Perspective for Single Atom Nanozymes Based Sensors: Advanced Materials, Sensing Mechanism, Selectivity Regulation, and Applications.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04496
Abstract: Nanozymes are a kind of nanomaterial mimicking enzyme catalytic activity, which has aroused extensive interest in the fields of biosensors, biomedicine, and climate and ecosystems management. However, due to the complexity of structures and composition… read more here.
Keywords: single atom; atom nanozymes; based sensors; mechanism ... See more keywords
Microwave-Assisted Rapid Synthesis of Near-Infrared Light-Responsive Pd Single-Atom Nanozymes for Colorimetric Detection of Acetylcholinesterase Activity.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c02343
Abstract: Single-atom nanozymes (SAzymes) have been widely utilized as promising sensing platforms for numerous analytical applications. However, the preparation of SAzymes usually needs tedious heating treatment, and their enzyme-mimicking activities are still difficult to modulate in… read more here.
Keywords: atom nanozymes; synthesis; microwave assisted; single atom ... See more keywords
Mated-Atom Nanozymes with Efficient Assisted NAD+ Replenishment for Skin Regeneration.
Sign Up to like & getrecommendations! Published in 2024 at "Nano letters"
DOI: 10.1021/acs.nanolett.4c00546
Abstract: Excessive accumulation of reduced nicotinamide adenine dinucleotide (NADH) within biological organisms is closely associated with many diseases. It remains a challenge to efficiently convert superfluous and detrimental NADH to NAD+. NADH oxidase (NOX) is a… read more here.
Keywords: atom nanozymes; man; skin regeneration; mated atom ... See more keywords
Unraveling the Proximity Effects of a Co-P Dual Site in Phosphorus-Coordinated Cobalt Single-Atom Nanozymes.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.5c18031
Abstract: Heteroatom coordination in single-atom nanozymes is considered a promising strategy to promote their enzyme-like performance, but the proximity effect of active metal sites and heteroatoms on their catalytic efficiency is still elusive. Herein, we demonstrate… read more here.
Keywords: dual site; atom nanozymes; site; single atom ... See more keywords
Reversible inhibition of the oxidase-like activity of Fe single-atom nanozymes for drug detection
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc00212d
Abstract: Mechanism research of nanozymes has always been of great interest since their emergence as outstanding mimics of friable natural enzymes. An important but rarely mentioned issue in mechanism research of nanozymology is the inhibitory effect… read more here.
Keywords: oxidase like; inhibition; single atom; atom nanozymes ... See more keywords