Atomistic Basis of Microtubule Dynamic Instability Assessed Via Multiscale Modeling
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-020-02715-6
Abstract: Microtubule “dynamic instability,” the abrupt switching from assembly to disassembly caused by the hydrolysis of GTP to GDP within the β subunit of the αβ-tubulin heterodimer, is necessary for vital cellular processes such as mitosis… read more here.
Keywords: atomistic basis; multiscale modeling; dynamic instability; microtubule dynamic ... See more keywords
Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab372
Abstract: Abstract Double-stranded DNA viruses package their genomes into pre-assembled capsids using virally-encoded ASCE ATPase ring motors. We present the first atomic-resolution crystal structure of a multimeric ring form of a viral dsDNA packaging motor, the… read more here.
Keywords: packaging motor; atomistic basis; basis force; motor ... See more keywords