IL-4Rα Inhibitor for Atopic Disease
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.06.046
Abstract: Dupilumab is a fully human IgG4 monoclonal antibody directed against the IL-4Rα subunit of IL-4 and IL-13 receptors. It blocks the signaling pathways of IL-4 and IL-13, key cytokines that drive type 2 inflammatory response.… read more here.
Keywords: atopic disease; atopic; inhibitor atopic;
Can biomarkers in umbilical cord blood predict atopic disease at school age?
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Research"
DOI: 10.1038/s41390-019-0686-z
Abstract: The prevalence of atopic diseases including atopic dermatitis, allergic rhinitis, allergic conjunctivitis, or their combination, and allergic asthma has reached epidemic proportions in Western societies and is still growing. In general, atopic diseases impact quality… read more here.
Keywords: age; ccl5; school age; atopic disease ... See more keywords
Pathways of atopic disease and neurodevelopmental impairment: assessing the evidence for infant antibiotics
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2022.2101450
Abstract: ABSTRACT Introduction Epidemiologic studies are starting to report associations between antibiotic use in early life and neurodevelopmental disorders. Through mechanisms within the gut microbiota-brain axis, indeed, it is plausible that infant antibiotic treatment plays a… read more here.
Keywords: disease neurodevelopmental; atopic disease; evidence infant; neurodevelopmental impairment ... See more keywords
Novel insights into central compartment atopic disease - a literature review.
Sign Up to like & getrecommendations! Published in 2023 at "Expert review of clinical immunology"
DOI: 10.1080/1744666x.2023.2192480
Abstract: INTRODUCTION Central compartment atopic disease (CCAD) is a newly recognized variant subtype of chronic rhinosinusitis (CRS). Although CCAD has been reported to be correlated with allergy, there is still a considerable gap in our knowledge… read more here.
Keywords: ccad; atopic disease; review; central compartment ... See more keywords
Ocular involvement in atopic disease: a review
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Ophthalmology"
DOI: 10.1097/icu.0000000000000532
Abstract: Purpose of review To provide a review of the potential sight-threatening sequelae associated with ocular involvement of atopic disease and to discuss the management of this chronic condition. Recent findings There has been a recognition… read more here.
Keywords: ocular involvement; ophthalmology; disease; involvement atopic ... See more keywords
Increased risk of osteoarthritis in patients with atopic disease
Sign Up to like & getrecommendations! Published in 2023 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-223640
Abstract: Objectives To determine the incidence of osteoarthrits (OA) in patients with atopic disease compared with matched non-exposed patients. Methods We conducted a retrospective cohort study with propensity score matching using claims data from Optum’s de-identified… read more here.
Keywords: non exposed; atopic disease; exposed patients; patients asthma ... See more keywords
Asthma is associated with carotid arterial injury in children: The Childhood Origins of Asthma (COAST) Cohort
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0204708
Abstract: Background Asthma is associated with an increased cardiovascular disease (CVD) risk in adults, but the impact of asthma and atopic conditions on CVD risk in children is less well established. We hypothesized that children in… read more here.
Keywords: atopic disease; arterial injury; asthma atopic; disease ... See more keywords
Quantitative glycoproteomics of human milk and association with atopic disease
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0267967
Abstract: The prevalence of allergic diseases and asthma is increasing rapidly worldwide, with environmental and lifestyle behaviors implicated as a reason. Epidemiological studies have shown that children who grow up on farms are at lower risk… read more here.
Keywords: quantitative glycoproteomics; disease; atopic disease; human milk ... See more keywords