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Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.04.044
Abstract: Aneurysmal subarachnoid hemorrhage is a common complication caused by an intracranial aneurysm that can lead to hemorrhagic stroke, brain damage, and death. Knowing this clinical situation, the purpose of this study was to develop a…
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Keywords:
atorvastatin calcium;
core shell;
microscopy;
shell nanofiber ... See more keywords
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Published in 2018 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2018.05.018
Abstract: Abstract In the present work, inclusion complexes of simvastatin (SIM), atorvastatin calcium (ATV) with hydroxypropyl-β-cyclodextrin (HP-β-CD) have been prepared using mechanochemistry technique to improve solubility of the two drugs and enhance their oral bioavailability. The…
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Keywords:
complexes simvastatin;
hydroxypropyl cyclodextrin;
atv;
atorvastatin calcium ... See more keywords
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Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.116066
Abstract: Abstract The reported solubility data of atorvastatin calcium in binary aqueous mixtures of acetone at various temperatures from 293.15 K to 328.15 K was reanalyzed based on some well-established cosolvency models and a number of…
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Keywords:
293 328;
comments concerning;
atorvastatin calcium;
solubility data ... See more keywords
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Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128564
Abstract: Abstract The charge-transfer interactions between n-electron donor, atorvastatin calcium (ATC) and the electron acceptors, 2,5-dihydroxy-1,4-benzoquinone (DHBQ), 1,2,5,8-tetrahydroxy-9,10-anthraquinone (quinalizarin, Quiz), and 2,4,6-trinitrophenol (picric acid, PA) as π-acceptors have been studied spectrophotometrically in methanol by giving highly…
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Keywords:
transfer complexes;
atorvastatin calcium;
picric acid;
quinalizarin ... See more keywords
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Published in 2020 at "Powder Diffraction"
DOI: 10.1017/s0885715620000147
Abstract: The crystal structure of atorvastatin calcium trihydrate (ACT) has been solved and refined using synchrotron X-ray powder diffraction data and optimized using density functional theory techniques. ACT crystallizes in space group P1 (#1) with a…
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Keywords:
atorvastatin calcium;
structure;
crystal structure;
structure atorvastatin ... See more keywords
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Published in 2018 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2018.1424209
Abstract: Abstract Context: Danshen tablets (DST), an effective traditional Chinese multi-herbal formula, are often combined with atorvastatin calcium (AC) for treating coronary heart disease in the clinic. Objective: This study investigated the effects of DST on…
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Keywords:
dst;
danshen tablets;
atorvastatin calcium;
potential mechanism ... See more keywords
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Published in 2022 at "European Journal of Mass Spectrometry"
DOI: 10.1177/14690667221105835
Abstract: Atorvastatin calcium is employed as front-line treatment for cardiovascular diseases. According to the international conference on harmonization (ICH) guideline ICH Q3D, elemental impurities can come into drug products from various sources. These elemental impurities do…
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Keywords:
mercury lead;
arsenic cadmium;
cadmium mercury;
elemental impurities ... See more keywords
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Published in 2022 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.38.8.5504
Abstract: Objectives: To analyze the effects of compound dextran combined with atorvastatin calcium on blood flow indexes, peroxidase 2 (Prx2) and endothelin-1 (ET-1) in patients with cerebral vasospasm (CVS) caused by subarachnoid hemorrhage (SAH). Methods: One…
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Keywords:
group;
cvs caused;
atorvastatin calcium;
compound dextran ... See more keywords
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Published in 2023 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.39.2.6721
Abstract: Objective: To evaluate the effect of nimodipine combined with atorvastatin calcium on the micro inflammation and oxidative stress levels in patients with cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) and its clinical implications. Methods: A…
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Keywords:
combined atorvastatin;
oxidative stress;
group;
nimodipine combined ... See more keywords
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Published in 2020 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201021666200217103302
Abstract: Biodegradable polymeric microneedles containing atorvastatin calcium were developed in order to improve the percutaneous absorption of the drug, useful for the treatment of hypercholesterolemia. The microneedles were made with poly (methyl vinyl ether-alt-maleic acid) as…
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Keywords:
methyl vinyl;
atorvastatin calcium;
vinyl ether;
poly methyl ... See more keywords
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Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13101658
Abstract: Atorvastatin Calcium (At-Ca) has pleiotropic effect as anti-inflammatory drug beside its main antihyperlipidemic action. Our study was conducted to modulate the anti-inflammatory effect of At-Ca to be efficiently sustained for longer time. Single oil-water emulsion…
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Keywords:
anti inflammatory;
vitro optimization;
atorvastatin calcium;
inflammatory effect ... See more keywords