An atorvastatin calcium and poly(L-lactide-co-caprolactone) core-shell nanofiber-covered stent to treat aneurysms and promote reendothelialization.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.04.044
Abstract: Aneurysmal subarachnoid hemorrhage is a common complication caused by an intracranial aneurysm that can lead to hemorrhagic stroke, brain damage, and death. Knowing this clinical situation, the purpose of this study was to develop a… read more here.
Keywords: atorvastatin calcium; core shell; microscopy; shell nanofiber ... See more keywords
Physicochemical characteristics of the complexes of simvastatin and atorvastatin calcium with hydroxypropyl-β-cyclodextrin produced by mechanochemical activation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2018.05.018
Abstract: Abstract In the present work, inclusion complexes of simvastatin (SIM), atorvastatin calcium (ATV) with hydroxypropyl-β-cyclodextrin (HP-β-CD) have been prepared using mechanochemistry technique to improve solubility of the two drugs and enhance their oral bioavailability. The… read more here.
Keywords: complexes simvastatin; hydroxypropyl cyclodextrin; atv; atorvastatin calcium ... See more keywords
Some comments concerning “Measurement and correlation of solubility data for atorvastatin calcium in pure and binary solvent systems from 293.15 K to 328.15 K”
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.116066
Abstract: Abstract The reported solubility data of atorvastatin calcium in binary aqueous mixtures of acetone at various temperatures from 293.15 K to 328.15 K was reanalyzed based on some well-established cosolvency models and a number of… read more here.
Keywords: 293 328; comments concerning; atorvastatin calcium; solubility data ... See more keywords
Synthesis, spectroscopic, thermal, structural investigations and biological activity studies of charge-transfer complexes of atorvastatin calcium with dihydroxy-p-benzoquinone, quinalizarin and picric acid
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128564
Abstract: Abstract The charge-transfer interactions between n-electron donor, atorvastatin calcium (ATC) and the electron acceptors, 2,5-dihydroxy-1,4-benzoquinone (DHBQ), 1,2,5,8-tetrahydroxy-9,10-anthraquinone (quinalizarin, Quiz), and 2,4,6-trinitrophenol (picric acid, PA) as π-acceptors have been studied spectrophotometrically in methanol by giving highly… read more here.
Keywords: transfer complexes; atorvastatin calcium; picric acid; quinalizarin ... See more keywords
Crystal structure of atorvastatin calcium trihydrate Form I (Lipitor®), (C33H34FN2O5)2Ca(H2O)3
Sign Up to like & getrecommendations! Published in 2020 at "Powder Diffraction"
DOI: 10.1017/s0885715620000147
Abstract: The crystal structure of atorvastatin calcium trihydrate (ACT) has been solved and refined using synchrotron X-ray powder diffraction data and optimized using density functional theory techniques. ACT crystallizes in space group P1 (#1) with a… read more here.
Keywords: atorvastatin calcium; structure; crystal structure; structure atorvastatin ... See more keywords
Effects of Danshen tablets on pharmacokinetics of atorvastatin calcium in rats and its potential mechanism
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2018.1424209
Abstract: Abstract Context: Danshen tablets (DST), an effective traditional Chinese multi-herbal formula, are often combined with atorvastatin calcium (AC) for treating coronary heart disease in the clinic. Objective: This study investigated the effects of DST on… read more here.
Keywords: dst; danshen tablets; atorvastatin calcium; potential mechanism ... See more keywords
Determination of arsenic, cadmium, mercury, lead and nickel as elemental impurities in atorvastatin calcium by inductively coupled mass spectrometer
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Mass Spectrometry"
DOI: 10.1177/14690667221105835
Abstract: Atorvastatin calcium is employed as front-line treatment for cardiovascular diseases. According to the international conference on harmonization (ICH) guideline ICH Q3D, elemental impurities can come into drug products from various sources. These elemental impurities do… read more here.
Keywords: mercury lead; arsenic cadmium; cadmium mercury; elemental impurities ... See more keywords
Analysis on efficacy of compound dextran combined with atorvastatin calcium in patients with CVS caused by SAH based on TCD blood flow indexes
Sign Up to like & getrecommendations! Published in 2022 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.38.8.5504
Abstract: Objectives: To analyze the effects of compound dextran combined with atorvastatin calcium on blood flow indexes, peroxidase 2 (Prx2) and endothelin-1 (ET-1) in patients with cerebral vasospasm (CVS) caused by subarachnoid hemorrhage (SAH). Methods: One… read more here.
Keywords: group; cvs caused; atorvastatin calcium; compound dextran ... See more keywords
Effect of nimodipine combined with atorvastatin calcium on microinflammation and oxidative stress levels in patients with cerebral vasospasm after subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2023 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.39.2.6721
Abstract: Objective: To evaluate the effect of nimodipine combined with atorvastatin calcium on the micro inflammation and oxidative stress levels in patients with cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) and its clinical implications. Methods: A… read more here.
Keywords: combined atorvastatin; oxidative stress; group; nimodipine combined ... See more keywords
Development of poly (methyl vinyl ether-alt-maleic acid) microneedles for transdermal delivery of atorvastatin calcium.
Sign Up to like & getrecommendations! Published in 2020 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201021666200217103302
Abstract: Biodegradable polymeric microneedles containing atorvastatin calcium were developed in order to improve the percutaneous absorption of the drug, useful for the treatment of hypercholesterolemia. The microneedles were made with poly (methyl vinyl ether-alt-maleic acid) as… read more here.
Keywords: methyl vinyl; atorvastatin calcium; vinyl ether; poly methyl ... See more keywords
A Novel Sustained Anti-Inflammatory Effect of Atorvastatin—Calcium PLGA Nanoparticles: In Vitro Optimization and In Vivo Evaluation
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DOI: 10.3390/pharmaceutics13101658
Abstract: Atorvastatin Calcium (At-Ca) has pleiotropic effect as anti-inflammatory drug beside its main antihyperlipidemic action. Our study was conducted to modulate the anti-inflammatory effect of At-Ca to be efficiently sustained for longer time. Single oil-water emulsion… read more here.
Keywords: anti inflammatory; vitro optimization; atorvastatin calcium; inflammatory effect ... See more keywords