Thiol‐based copper handling by the copper chaperone Atox1
Sign Up to like & getrecommendations! Published in 2017 at "IUBMB Life"
DOI: 10.1002/iub.1620
Abstract: Human antioxidant protein 1 (Atox1) plays a crucial role in cellular copper homeostasis. Atox1 captures cytosolic copper for subsequent transfer to copper pumps in trans Golgi network, thereby facilitating copper supply to various copper‐dependent oxidereductases… read more here.
Keywords: atox1; based copper; copper handling; thiol based ... See more keywords
Crystal Structure of the Human Copper Chaperone ATOX1 Bound to Zinc Ion
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101494
Abstract: The bioavailability of copper (Cu) in human cells may depend on a complex interplay with zinc (Zn) ions. We investigated the ability of the Zn ion to target the human Cu-chaperone Atox1, a small cytosolic… read more here.
Keywords: chaperone atox1; copper; zinc; atox1 ... See more keywords