Articles with "atp adenosine" as a keyword



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Corrigendum to "Extracellular ATP and adenosine: The yin and yang in immune responses?" [Molecular Aspects of Medicine 55 (2017) 9-19].

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Published in 2017 at "Molecular aspects of medicine"

DOI: 10.1016/j.mam.2017.08.003

Abstract: The authors regret that they did not mention this funding: This project has received funding from the Marie Curie International Research Staff Exchange Scheme with the 7th European Community Framework Program under grant agreement No.… read more here.

Keywords: medicine; molecular aspects; corrigendum extracellular; extracellular atp ... See more keywords
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Targeting CD39 in cancer

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Published in 2020 at "Nature Reviews Immunology"

DOI: 10.1038/s41577-020-0376-4

Abstract: The ATP–adenosine pathway functions as a key modulator of innate and adaptive immunity within the tumour microenvironment. Consequently, multiple clinical strategies are being explored to target this pathway for the treatment of cancer; in particular,… read more here.

Keywords: immunity; adenosine pathway; pathway; atp adenosine ... See more keywords
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Conversion of extracellular ATP into adenosine: a master switch in renal health and disease

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Published in 2020 at "Nature Reviews Nephrology"

DOI: 10.1038/s41581-020-0304-7

Abstract: ATP and its ultimate degradation product adenosine are potent extracellular signalling molecules that elicit a variety of pathophysiological functions in the kidney through the activation of P2 and P1 purinergic receptors, respectively. Extracellular purines can… read more here.

Keywords: atp adenosine; extracellular atp; disease; kidney ... See more keywords
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Disruption of the ATP/adenosine balance in CD39−/− mice is associated with handling‐induced seizures

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Published in 2017 at "Immunology"

DOI: 10.1111/imm.12798

Abstract: Seizures are due to excessive, synchronous neuronal firing in the brain and are characteristic of epilepsy, the fourth most prevalent neurological disease. We report handling‐induced and spontaneous seizures in mice deficient for CD39, a cell‐surface… read more here.

Keywords: cd39 mice; induced seizures; handling induced; atp adenosine ... See more keywords
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Inhibitory Effects of ATP and Adenosine on Cholangiocarcinoma Cell Proliferation and Motility.

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Published in 2017 at "Anticancer research"

DOI: 10.21873/anticanres.11725

Abstract: BACKGROUND/AIM Inhibitory effects of extracellular nucleotides have been investigated in many types of cancers. Herein, we aimed to determine the effects of ATP and adenosine and their receptor profile on cholangiocarcinoma (CCA) cells. MATERIALS AND… read more here.

Keywords: inhibitory effects; proliferation; motility; atp adenosine ... See more keywords