Histone Octamer Structure Is Altered Early in ISW2 ATP-Dependent Nucleosome Remodeling.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.05.106
Abstract: Nucleosomes are the fundamental building blocks of chromatin that regulate DNA access and are composed of histone octamers. ATP-dependent chromatin remodelers like ISW2 regulate chromatin access by translationally moving nucleosomes to different DNA regions. We find… read more here.
Keywords: isw2; octamer structure; atp dependent; early isw2 ... See more keywords
ATP-dependent hydroxylation of an unactivated primary carbon with water
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17675-7
Abstract: Enzymatic hydroxylation of unactivated primary carbons is generally associated with the use of molecular oxygen as co-substrate for monooxygenases. However, in anaerobic cholesterol-degrading bacteria such as Sterolibacterium denitrificans the primary carbon of the isoprenoid side… read more here.
Keywords: hydroxylation; water; atp dependent; unactivated primary ... See more keywords
Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19700-1
Abstract: Over the last 3 decades ATP-dependent chromatin remodelers have been thought to recognize chromatin at the level of single nucleosomes rather than higher-order organization of more than one nucleosome. We show the yeast ISW1a remodeler… read more here.
Keywords: chromatin; dinucleosome specificity; atp dependent; transcription regulation ... See more keywords
MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Sign Up to like & getrecommendations! Published in 2021 at "Nature communications"
DOI: 10.1038/s41467-021-27062-5
Abstract: Our innate immune responses to viral RNA are vital defenses. Long cytosolic double-stranded RNA (dsRNA) is recognized by MDA5. The ATPase activity of MDA5 contributes to its dsRNA binding selectivity. Mutations that reduce RNA selectivity… read more here.
Keywords: variant m854k; rna; atp dependent; disease ... See more keywords
Bacteriophage origin of some minimal ATP-dependent DNA ligases: a new structure from Burkholderia pseudomallei with striking similarity to Chlorella virus ligase
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-98155-w
Abstract: DNA ligases, the enzymes responsible for joining breaks in the phosphodiester backbone of DNA during replication and repair, vary considerably in size and structure. The smallest members of this enzyme class carry out their functions… read more here.
Keywords: dna; atp dependent; virus; dna ligases ... See more keywords
Mitochondria regulate cardiac contraction through ATP-dependent and independent mechanisms
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Research"
DOI: 10.1080/10715762.2018.1453137
Abstract: Abstract The multipurpose organelle mitochondria play an essential role(s) in controlling cardiac muscle contraction. Mitochondria, not only function as the powerhouses and the energy source of myocytes but also modulate intracellular Ca2+ homeostasis, the production… read more here.
Keywords: mitochondria regulate; cardiac contraction; atp dependent; regulate cardiac ... See more keywords
The ATP-dependent chromatin remodeler Chd1 is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx636
Abstract: Chd1 (Chromodomain Helicase DNA Binding Protein 1) is a conserved ATP-dependent chromatin remodeler that maintains the nucleosomal structure of chromatin, but the determinants of its specificity and its impact on gene expression are not well… read more here.
Keywords: chd1; chromatin; atp dependent; chromatin remodeler ... See more keywords
Dose-dependent Spasmolytic, Bronchodilator, and Hypotensive Activities of Panicum miliaceum L.
Sign Up to like & getrecommendations! Published in 2022 at "Dose-Response"
DOI: 10.1177/15593258221079592
Abstract: Panicum miliaceum L. is a medicinally effective plant used in indigenous system of medicine for a variety of ailments. However, there is no comprehensive study explaining its effectiveness in gastrointestinal tract, respiratory, and cardiovascular system… read more here.
Keywords: spasmolytic bronchodilator; dose dependent; atp dependent; panicum miliaceum ... See more keywords
Cleavage-Dependent Activation of ATP-Dependent Protease HslUV from Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2020 at "Molecules and Cells"
DOI: 10.14348/molcells.2020.0074
Abstract: HslUV is a bacterial heat shock protein complex consisting of the AAA+ ATPase component HslU and the protease component HslV. HslV is a threonine (Thr) protease employing the N-terminal Thr residue in the mature protein… read more here.
Keywords: staphylococcus aureus; protease; atp dependent; hsluv ... See more keywords
The ATP-dependent pathways and human diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220322104552
Abstract: Adenosine triphosphate (ATP) is one of the most important molecules of life, present both, inside the cells and extracellularly. It is essential building block for nucleic acids biosynthesis and crucial intracellular energy storage. However, one… read more here.
Keywords: chemistry; atp dependent; pathways human; dependent pathways ... See more keywords
ATP-dependent conformational change in ABC-ATPase RecF serves as a switch in DNA repair.
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.2210/pdb5z69/pdb
Abstract: RecF is a principal member of the RecF pathway. It interacts with RecO and RecR to initiate homologous recombination by loading RecA recombinases on single-stranded DNA and displacing single-stranded DNA-binding proteins. As an ATP-binding cassette… read more here.
Keywords: dna; dimerization; recf; atp dependent ... See more keywords