LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "atp hydrolysis" as a keyword



Elucidating the Uncoupling of ATP Hydrolysis and Ca2+ Transport in SERCA by Sarcolipin

Sign Up to like & get
recommendations! Published in 2017 at "Biophysical Journal"

DOI: 10.1016/j.bpj.2016.11.2708

Abstract: The activity of the sarco(endo)plasmic reticulum Ca2+ -ATPase (SERCA), which plays a key role in muscle contraction and relaxation, is regulated by sarcolipin (SLN), a 31-residue transmembrane peptide. Sarcolipin has been shown to uncouple ATP… read more here.

Keywords: atp hydrolysis; serca; hydrolysis ca2; ca2 transport ... See more keywords
Photo from wikipedia

Insights into the Cooperative Nature of ATP Hydrolysis in Actin Filaments.

Sign Up to like & get
recommendations! Published in 2018 at "Biophysical journal"

DOI: 10.1016/j.bpj.2018.08.034

Abstract: Actin filaments continually assemble and disassemble within a cell. Assembled filaments "age" as a bound nucleotide ATP within each actin subunit quickly hydrolyzes followed by a slower release of the phosphate Pi, leaving behind a… read more here.

Keywords: atp hydrolysis; cooperative nature; hydrolysis; actin filaments ... See more keywords

Yeast Chd1p Unwraps the Exit Side DNA upon ATP Binding to Facilitate the Nucleosome Translocation Occurring upon ATP Hydrolysis.

Sign Up to like & get
recommendations! Published in 2020 at "Biochemistry"

DOI: 10.1021/acs.biochem.0c00747

Abstract: Chromodomain-helicase-DNA-binding protein 1 (CHD1) remodels chromatin by translocating nucleosomes along DNA, but its mechanism remains poorly understood. We use single-molecule fluorescence experiments to clarify the mechanism by which yeast CHD1 (Chd1p) remodels nucleosomes. We find… read more here.

Keywords: atp hydrolysis; nucleosome translocation; upon atp; dna ... See more keywords

Determination of Initial Rates of Lipopolysaccharide Transport

Sign Up to like & get
recommendations! Published in 2024 at "Biochemistry"

DOI: 10.1021/acs.biochem.4c00379

Abstract: Nonvesicular lipid trafficking pathways are an important process in every domain of life. The mechanisms of these processes are poorly understood in part due to the difficulty in kinetic characterization. One important class of glycolipids,… read more here.

Keywords: outer membrane; rate lps; lps transport; atp hydrolysis ... See more keywords

Role of the Conserved DECH-Box Cysteine in Coupling Hepatitis C Virus Helicase-Catalyzed ATP Hydrolysis to RNA Unwinding.

Sign Up to like & get
recommendations! Published in 2018 at "Biochemistry"

DOI: 10.1021/acs.biochem.8b00796

Abstract: DECH-box proteins are a subset of DExH/D-box superfamily 2 helicases possessing a conserved Asp-Glu-Cys-His motif in their ATP binding site. The conserved His helps position the Asp and Glu residues, which coordinate the divalent metal… read more here.

Keywords: cys; atp hydrolysis; role; helicase ... See more keywords

Molecular Basis of RNA-Driven ATP Hydrolysis in DExH-Box Helicases.

Sign Up to like & get
recommendations! Published in 2023 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.2c11980

Abstract: The spliceosome machinery catalyzes precursor messenger (pre-m)RNA splicing. In each cycle, the spliceosome experiences massive compositional and conformational remodeling fueled by the concerted action of specific RNA-dependent ATPases/helicases. Intriguingly, these enzymes are allosterically activated to… read more here.

Keywords: dexh box; rna; atp hydrolysis;

Spectroscopic glimpses of the transition state of ATP hydrolysis trapped in a bacterial DnaB helicase

Sign Up to like & get
recommendations! Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-25599-z

Abstract: The ATP hydrolysis transition state of motor proteins is a weakly populated protein state that can be stabilized and investigated by replacing ATP with chemical mimics. We present atomic-level structural and dynamic insights on a… read more here.

Keywords: state; bacterial dnab; atp hydrolysis; transition state ... See more keywords
Photo from wikipedia

ATP hydrolysis and nucleotide exit enhance maltose translocation in the MalFGK2E importer

Sign Up to like & get
recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-89556-y

Abstract: ATP binding cassette (ABC) transporters employ ATP hydrolysis to harness substrate translocation across membranes. The Escherichia coli MalFGK2E maltose importer is an example of a type I ABC importer and a model system for this… read more here.

Keywords: hydrolysis nucleotide; importer; atp hydrolysis; hydrolysis ... See more keywords
Photo by vlisidis from unsplash

Hierarchical dynamics in allostery following ATP hydrolysis monitored by single molecule FRET measurements and MD simulations†

Sign Up to like & get
recommendations! Published in 2021 at "Chemical Science"

DOI: 10.1039/d0sc06134d

Abstract: We report on a study that combines advanced fluorescence methods with molecular dynamics (MD) simulations to cover timescales from nanoseconds to milliseconds for a large protein. This allows us to delineate how ATP hydrolysis in… read more here.

Keywords: protein; hierarchical dynamics; atp hydrolysis; allostery following ... See more keywords

Differential regulation of ATP hydrolysis of RIG-I-like receptors by transactivation response RNA-binding protein

Sign Up to like & get
recommendations! Published in 2023 at "Bioscience Reports"

DOI: 10.1042/bsr20222152

Abstract: Abstract Retinoic acid inducible gene (RIG)-I-like receptors (RLRs), including RIG-I, melanoma differentiation associated-5 (MDA5), and laboratory of genetics and physiology 2 (LGP2), play pivotal roles in viral RNA sensing to initiate antiviral interferon (IFN) responses.… read more here.

Keywords: rna; trbp; atp hydrolysis; response ... See more keywords

Road-blocker HSP disease mutation disrupts pre-organization for ATP hydrolysis in kinesin through a second sphere control

Sign Up to like & get
recommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2215170120

Abstract: Significance Kinesin, an amazing biological machine, converts chemical energy from the ATP hydrolysis into mechanical energy to perform different cellular activities. Several single-point gene-level mutations in the neuronal kinesin motor (KIF5A) are linked to a… read more here.

Keywords: pre organization; kinesin second; second sphere; atp hydrolysis ... See more keywords