Loss of SLC25A11 causes suppression of NSCLC and melanoma tumor formation
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.01.036
Abstract: Background Fast growing cancer cells require greater amounts of ATP than normal cells. Although glycolysis was suggested as a source of anabolic metabolism based on lactate production, the main source of ATP to support cancer… read more here.
Keywords: slc25a11; nsclc melanoma; cancer cells; atp production ... See more keywords
Lactate-Mediated Protection of Retinal Ganglion Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.03.005
Abstract: Loss of retinal ganglion cells (RGCs) is a leading cause of blinding conditions. The purpose of this study was to evaluate the effect of extracellular l-lactate on RGC survival facilitated through lactate metabolism and ATP… read more here.
Keywords: retinal ganglion; lactate; ganglion cells; rgc survival ... See more keywords
Respiratory ATP cost and benefit of arbuscular mycorrhizal symbiosis with Nicotiana tabacum at different growth stages and under salinity.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of plant physiology"
DOI: 10.1016/j.jplph.2017.08.012
Abstract: Growth and maintenance partly depend on both respiration and ATP production during oxidative phosphorylation in leaves. Under stress, ATP is needed to maintain the accumulated biomass. ATP production mostly proceeds from the cytochrome oxidase pathway… read more here.
Keywords: atp; arbuscular mycorrhizal; different growth; atp production ... See more keywords
Urocortin stimulates ERK1/2 phosphorylation and proliferation but reduces ATP production of MCF7 breast cancer cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2022.111610
Abstract: Urocortins are members of the stress-related corticotropin-releasing factor family. Small amounts of them are present in the circulation and they are produced locally in various tissues of higher vertebrates. Aside from regulating circulation, or food… read more here.
Keywords: breast cancer; cancer cells; atp production; proliferation ... See more keywords
Decreased ATP production and myocardial contractile reserve in metabolic heart disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2018.01.017
Abstract: Metabolic syndrome is a cluster of obesity-related metabolic abnormalities that lead to metabolic heart disease (MHD) with left ventricular pump dysfunction. Although MHD is thought to be associated with myocardial energetic deficiency, two key questions… read more here.
Keywords: hfhs hearts; heart; atp production;
Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly.
Sign Up to like & getrecommendations! Published in 2021 at "Nature cell biology"
DOI: 10.1038/s41556-021-00760-4
Abstract: Cells respond to stress by blocking translation, rewiring metabolism and forming transient messenger ribonucleoprotein assemblies called stress granules (SGs). After stress release, re-establishing homeostasis and disassembling SGs requires ATP-consuming processes. However, the molecular mechanisms whereby… read more here.
Keywords: metabolism; atp production; stress; amyloids pyruvate ... See more keywords
Berberine chloride (dual topoisomerase I and II inhibitor) modulate mitochondrial uncoupling protein (UCP1) in molecular docking and dynamic with in-vitro cytotoxic and mitochondrial ATP production
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2021.2024255
Abstract: Abstract Obesity initiates numerous diseases like cardiovascular, metabolic, and type 2 diabetes, and obesity is a vital cause of death worldwide. Plants are necessary to the source of life. Several drug compounds isolated from plants… read more here.
Keywords: berberine chloride; mitochondrial uncoupling; berberine; chloride dual ... See more keywords
Aerobic scope falls to nil at Pcrit and anaerobic ATP production increases below Pcrit in the tidepool sculpin, Oligocottus maculosus
Sign Up to like & getrecommendations! Published in 2022 at "Biology Letters"
DOI: 10.1098/rsbl.2022.0342
Abstract: The critical oxygen tension of whole-animal oxygen uptake rate, or Pcrit, has historically been defined as the oxygen partial pressure (PO2) at which aerobic scope falls to zero and further declines in PO2 require substrate-level… read more here.
Keywords: scope falls; aerobic scope; scope; atp production ... See more keywords
H2O2‐induced oxidative stress disrupts mitochondrial functions and impairs migratory potential of human epidermal melanocytes
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Dermatology"
DOI: 10.1111/exd.14134
Abstract: Reactive oxygen species (ROS) have already been demonstrated to impede the migratory ability in non‐melanocytic cell lines by depleting mitochondrial ATP production. Therefore, understanding the mitochondrial metabolic response to migration in the presence of ROS… read more here.
Keywords: migratory potential; atp; migration; atp production ... See more keywords
Lichen fungi do not depend on the alga for ATP production: A comment on Pogoda et al. (2018)
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Ecology"
DOI: 10.1111/mec.16010
Abstract: Lichen fungi live in a symbiotic association with unicellular phototrophs and most have no known aposymbiotic stage. A recent study in Molecular Ecology postulated that some of them have lost mitochondrial oxidative phosphorylation and rely… read more here.
Keywords: alga atp; fungi depend; depend alga; atp production ... See more keywords
Biological characteristics and metabolic profile of canine mesenchymal stem cells isolated from adipose tissue and umbilical cord matrix
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0247567
Abstract: Despite the increasing demand of cellular therapies for dogs, little is known on the differences between adult and fetal adnexa canine mesenchymal stem cells (MSCs), and data on their metabolic features are lacking. The present… read more here.
Keywords: canine mesenchymal; atp production; mscs; mesenchymal stem ... See more keywords