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   Articles with "atp release" as a keyword



Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

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recommendations! Published in 2025 at "FEBS Letters"

DOI: 10.1002/1873-3468.70166

Abstract: The protective effects of imeglimin, a recently approved antidiabetic agent, against liver fibrosis have not been previously evaluated. In this study, we demonstrated that 8‐week administration of imeglimin attenuated immune cell infiltration and reduced collagen… read more here.

Keywords: liver fibrosis; atp release; atp; hepatic stellate ... See more keywords
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Novel insights into role of miR‐320a‐VDAC1 axis in astrocyte‐mediated neuronal damage in neuroAIDS

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recommendations! Published in 2017 at "Glia"

DOI: 10.1002/glia.23089

Abstract: Astroglia are indispensable component of the tripartite synapse ensheathing innumerous soma and synapses. Its proximity to neurons aids the regulation of neuronal functions, health and survival through dynamic neuroglia crosstalk. Susceptibility of astrocyte to HIV‐1… read more here.

Keywords: hiv; vdac1; hiv tat; atp release ... See more keywords
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Fluorescent Labeling and Quantification of Vesicular ATP Release Using Live Cell Imaging.

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recommendations! Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9717-6_15

Abstract: Adenosine triphosphate (ATP) is actively transported into vesicles for purinergic neurotransmission by the vesicular nucleotide transporter, VNUT, encoded by the gene, solute carrier 17, member 9 (SLC17A9). In this chapter, methods are described for fluorescent… read more here.

Keywords: vesicular atp; atp; live cell; atp release ... See more keywords
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Pannexin 1 channels and ATP release in epilepsy: two sides of the same coin : The contribution of pannexin-1, connexins, and CALHM ATP-release channels to purinergic signaling.

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recommendations! Published in 2021 at "Purinergic signalling"

DOI: 10.1007/s11302-021-09818-2

Abstract: Purinergic signaling mediated by ATP and its metabolites contributes to various brain physiological processes as well as to several pathological conditions, including neurodegenerative and neurological disorders, such as epilepsy. Among the different ATP release pathways,… read more here.

Keywords: epilepsy; pannexin channels; atp release; pannexin ... See more keywords

ATP Release by Red Blood Cells under Flow: Model and Simulations.

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recommendations! Published in 2018 at "Biophysical journal"

DOI: 10.1016/j.bpj.2018.09.033

Abstract: ATP is a major player as a signaling molecule in blood microcirculation. It is released by red blood cells (RBCs) when they are subjected to shear stresses large enough to induce a sufficient shape deformation.… read more here.

Keywords: red blood; model; atp release; blood cells ... See more keywords
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Propidium uptake and ATP release in A549 cells share similar transport mechanisms.

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recommendations! Published in 2022 at "Biophysical journal"

DOI: 10.1016/j.bpj.2022.04.007

Abstract: The lipid bilayer of eukaryotic cells' plasma membrane is almost impermeable to small ions and large polar molecules but its miniscule basal permeability in intact cells is poorly characterized. This report describes the intrinsic membrane… read more here.

Keywords: atp; membrane; atp release; cell ... See more keywords

Lysosome exocytosis is involved in astrocyte ATP release after oxidative stress induced by H2O2

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recommendations! Published in 2019 at "Neuroscience Letters"

DOI: 10.1016/j.neulet.2019.03.046

Abstract: BACKGROUND AND PURPOSE Studies demonstrated that oxidative damage decreased intracellular ATP level in astrocytes. However, the pathway mediated ATP level decrease is obscure. Our previous study found intracellular ATP could be released via lysosome exocytosis… read more here.

Keywords: lysosome exocytosis; atp release; exocytosis; release oxidative ... See more keywords

Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress

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recommendations! Published in 2023 at "ACS Chemical Neuroscience"

DOI: 10.1021/acschemneuro.2c00810

Abstract: Increased ATP release and its extracellular catabolism through CD73 (ecto-5′-nucleotidase) lead to the overactivation of adenosine A2A receptors (A2AR), which occurs in different brain disorders. A2AR blockade blunts mood and memory dysfunction caused by repeated… read more here.

Keywords: cd73 mediated; cd73; stress; release ... See more keywords

Diabetes‐induced alterations in urothelium function: Enhanced ATP release and nerve‐evoked contractions in the streptozotocin rat bladder

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recommendations! Published in 2018 at "Clinical and Experimental Pharmacology and Physiology"

DOI: 10.1111/1440-1681.13003

Abstract: Up to 80% of patients with diabetes mellitus develop lower urinary tract complications, most commonly diabetic bladder dysfunction (DBD). The aim of this study was to investigate the impact of diabetes on the function of… read more here.

Keywords: nerve evoked; function; bladder; evoked contractions ... See more keywords

Pannexin‐1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration

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recommendations! Published in 2019 at "Acta Physiologica"

DOI: 10.1111/apha.13360

Abstract: Extracellular ATP signalling is involved in many physiological and pathophysiological processes in several tissues, including adipose tissue. Adipocytes have crucial functions in lipid and glucose metabolism and they express purinergic receptors. However, the sources of… read more here.

Keywords: mediated atp; pannexin mediated; extracellular atp; release adipocytes ... See more keywords

ATP release and metabolism by human and guinea pig airways and P2X receptor-dependent effects on bronchopulmonary vagal afferent nerve subtypes.

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recommendations! Published in 2025 at "British journal of pharmacology"

DOI: 10.1111/bph.70238

Abstract: BACKGROUND AND PURPOSE ATP-dependent activation of P2X receptors has been implicated in chronic cough. The mechanisms of ATP release in cough and how P2X-receptor engagement produces cough hypersensitivity are not clear. It is also unclear… read more here.

Keywords: p2x receptor; release; atp release; guinea ... See more keywords