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Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22849
Abstract: Growing cannabis efficacy, usage frequency, legal supply, and declining awareness of danger recently led to expanded United States cannabis exposure. In turn, cannabis use among elderly people over 50 has more than tripled in a…
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Keywords:
abnormal cannabidiol;
atp sensitive;
sensitive channel;
preterm infants ... See more keywords
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Published in 2020 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-020-04729-5
Abstract: We studied the influence of intraperitoneal injection of ATP-sensitive potassium channels inhibitor glibenclamide in doses of 0.01, 0.1, 1, and 10 mg/kg on the effects of a new pyrazolo[C]pyridine derivative GIZh-72 (4,6-dimethyl-2-(4-chlorphenyl)-2,3-dihydro-1Hpyrazolo[ 4,3-C]pyridine-3-on, chloral hydrate;…
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Keywords:
potassium channels;
sensitive potassium;
effects new;
atp sensitive ... See more keywords
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Published in 2020 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2020.100559
Abstract: Abstract Epilepsy is characterized by repeated spontaneous seizures and remains untreatable due to its complicate pathogenesis. Low-dose hydrogen sulfide (H2S) has been shown to exert antiepileptic and protective effects in the central nervous system, but…
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Keywords:
sensitive potassium;
h2s donor;
carbazole based;
atp sensitive ... See more keywords
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Published in 2017 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2017.01.006
Abstract: OBJECTIVE Potassium channels of the ATP-sensitive family (KATP channel) are inhibited by increase in intracellular ATP. Electrophysiological studies have demonstrated that the kinetics and pharmacological properties of KATP channels vary among different tissues, suggesting structurally…
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Keywords:
periodontal ligament;
atp sensitive;
human pdl;
channel ... See more keywords
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Published in 2021 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2021.01.003
Abstract: In the past decade, there was an increasing interest in the therapeutic potential targeting ATP-sensitive potassium (KATP) channels for an effective treatment of Parkinson's disease (PD). KATP channels are widely expressed in the central nervous…
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Keywords:
sensitive potassium;
katp channels;
atp sensitive;
parkinson disease ... See more keywords
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Published in 2019 at "Drug research"
DOI: 10.1055/a-0806-7207
Abstract: A study of potassium channels correlates the fundamentals of mechanistic pathways and various physiological functions. The knowledge of these pathways provides the background, how to determine unit cell functions and to affect cardio protection. ATP…
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Keywords:
potassium channels;
potassium;
sensitive potassium;
atp sensitive ... See more keywords
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Published in 2023 at "Immunopharmacology and immunotoxicology"
DOI: 10.1080/08923973.2023.2201659
Abstract: BACKGROUND Methotrexate (MTX) is a commonly used chemotherapeutic agent; however, its clinical use is challenged by various types of injuries, including hepatotoxic side effects. Therefore, finding new protective drugs against MTX-induced toxicities is a critical…
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Keywords:
enos glycoprotein;
liver injury;
atp sensitive;
potassium channel ... See more keywords
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Published in 2021 at "National Science Review"
DOI: 10.1093/nsr/nwaa198
Abstract: Abstract The current aggregation-induced emission luminogens (AIEgens) sometimes suffer from poor targeting selectivity due to undesirable aggregation in the hydrophilic biosystem with ‘always-on’ fluorescence or unspecific aggregation in the lipophilic organelle with prematurely activated fluorescence.…
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Keywords:
aggregation;
sensitive potassium;
endoplasmic reticulum;
potassium katp ... See more keywords
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Published in 2017 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.13756
Abstract: ATP‐sensitive K+ (K‐ATP) channels play significant roles in regulating the excitability of dopamine neurons in the substantia nigra zona compacta (SNC). We showed previously that K‐ATP channel function is up‐regulated by AMP‐activated protein kinase (AMPK).…
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Keywords:
vta;
atp sensitive;
nigra zona;
ventral tegmental ... See more keywords
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Published in 2019 at "Cephalalgia"
DOI: 10.1177/0333102419888490
Abstract: Introduction Levcromakalim opens ATP-sensitive potassium channels (KATP channel) and induces head pain in healthy volunteers and migraine headache in migraine patients, but no pain in other parts of the body. KATP channels are expressed in…
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Keywords:
potassium channels;
sensitive potassium;
placebo forehead;
atp sensitive ... See more keywords
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Published in 2022 at "eNeuro"
DOI: 10.1523/eneuro.0120-22.2022
Abstract: Abstract Arginine vasopressin (AVP) serves as a neuromodulator in the brain. The hippocampus is one of the major targets for AVP, as it has been demonstrated that the hippocampus receives vasopressinergic innervation and expresses AVP…
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Keywords:
sensitive channels;
arginine vasopressin;
plc;
atp sensitive ... See more keywords