Sign Up to like & get
recommendations!
0
Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-00618-6
Abstract: Menkes disease (MD) is caused by mutations in ATP7A, encoding a copper-transporting P-type ATPase which exhibits copper-dependent trafficking. ATP7A is found in the Trans-Golgi Network (TGN) at low copper concentrations, and in the post-Golgi compartments…
read more here.
Keywords:
atp7a;
tgn;
copper;
atp7a missense ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11961-z
Abstract: Copper (Cu) is an essential cofactor for various enzymatic activities including mitochondrial electron transport, iron mobilization, and peptide hormone maturation. Consequently, Cu dysregulation is associated with fatal neonatal disease, liver and cardiac dysfunction, and anemia.…
read more here.
Keywords:
homeostasis;
regulation atp7a;
atp7a;
atp7a abundance ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.827891
Abstract: Chemotherapy resistance represents a formidable obstacle in advanced or metastatic colorectal cancer (CRC) patients. It is reported that ATPase copper transporting alpha (ATP7A) plays an important role in chemotherapy resistance in CRC. Here, we identified…
read more here.
Keywords:
resistance crc;
resistance;
atp7a;
crc ... See more keywords