Colonic Potassium Absorption and Secretion in Health and Disease.
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DOI: 10.1002/cphy.c170030
Abstract: The colon has large capacities for K+ absorption and K+ secretion, but its role in maintaining K+ homeostasis is often overlooked. For many years, passive diffusion and/or solvent drag were thought to be the primary… read more here.
Keywords: absorption; apical atpase; atpase; absorption secretion ... See more keywords
Structure and Function of Na,K-ATPase-The Sodium-Potassium Pump.
Sign Up to like & getrecommendations! Published in 2021 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c200018
Abstract: Na,K-ATPase is an ubiquitous enzyme actively transporting Na-ions out of the cell in exchange for K-ions, thereby maintaining their concentration gradients across the cell membrane. Since its discovery more than six decades ago the Na-pump… read more here.
Keywords: function atpase; atpase sodium; structure function; atpase ... See more keywords
Frequent mutations of genes encoding vacuolar H+‐ATPase components in granular cell tumors
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DOI: 10.1002/gcc.22727
Abstract: Granular cell tumors (GCTs) are rare mesenchymal tumors that exhibit a characteristic morphology and a finely granular cytoplasm. The genetic alterations responsible for GCT tumorigenesis had been unknown until recently, when loss‐of‐function mutations of ATP6AP1… read more here.
Keywords: atpase components; atpase; genes encoding; granular cell ... See more keywords
Roles for H+/K+‐ATPase and zinc transporter 3 in cAMP‐mediated lysosomal acidification in bafilomycin A1‐treated astrocytes
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DOI: 10.1002/glia.23952
Abstract: Vacuolar ATPase (v‐ATPase) is the main proton pump that acidifies vesicles such as lysosomes. Disruption in the lysosomal localization of v‐ATPase leads to lysosomal dysfunction, thus contributing to the pathogenesis of lysosomal storage disorders and… read more here.
Keywords: camp; atpase; mediated lysosomal; camp mediated ... See more keywords
The adenosine monophosphate–activated protein kinase—vacuolar adenosine triphosphatase–pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30029
Abstract: Liver fibrosis and cirrhosis are characterized by activation of hepatic stellate cells (HSCs), which is associated with higher intracellular pH (pHi). The vacuolar H+ adenosine‐triphosphatase (v‐ATPase) multisubunit complex is a key regulator of pHi homeostasis.… read more here.
Keywords: atpase; ampk; activation; adenosine ... See more keywords
Formate and potassium ions affect Escherichia coli proton ATPase activity at low pH during mixed carbon fermentation
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DOI: 10.1002/iub.2219
Abstract: Escherichia coli is able to ferment not only single but also mixtures of carbon sources. The formate metabolism and effect of formate on various enzymes have been extensively studied during sole glucose but not mixed… read more here.
Keywords: atpase; potassium ions; formate; atpase activity ... See more keywords
N‐linked glycosylation of a subunit isoforms is critical for vertebrate vacuolar H+‐ATPase (V‐ATPase) biosynthesis
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DOI: 10.1002/jcb.26250
Abstract: The a subunit of the V0 membrane‐integrated sector of human V‐ATPase has four isoforms, a1‐a4, with diverse and crucial functions in health and disease. They are encoded by four conserved paralogous genes, and their vertebrate… read more here.
Keywords: atpase; linked glycosylation; subunit isoforms; subunit ... See more keywords
Tubulin–Na+ ,K +‐ATPase interaction: Involvement in enzymatic regulation and cellular function
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DOI: 10.1002/jcp.27610
Abstract: A new function for tubulin was described by our laboratory: acetylated tubulin forms a complex with Na+,K +‐ATPase (NKA) and inhibits its activity. This process was shown to be a regulatory factor of physiological importance… read more here.
Keywords: acetylated tubulin; atpase; physiology; function ... See more keywords
Na,K‐ATPase: A murzyme facilitating thermodynamic equilibriums at the membrane‐interface
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30925
Abstract: The redox metabolic paradigm of murburn concept advocates that diffusible reactive species (DRS, particularly oxygen‐centric radicals) are mainstays of physiology, and not mere pathological manifestations. The murburn purview of cellular function also integrates the essential… read more here.
Keywords: atpase murzyme; thermodynamic equilibriums; murzyme facilitating; physiology ... See more keywords
Role of unique loops in oligomerization and ATPase function of Plasmodium falciparum gyrase B
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DOI: 10.1002/pro.4217
Abstract: DNA gyrase is an ATP dependent Type IIA topoisomerase that is unique to prokaryotes. Interestingly DNA gyrase has also been found in the apicoplasts of apicomplexan parasites like Plasmodium falciparum (Pf) the causative agent of… read more here.
Keywords: pfgyrbn; gyrase; region; atpase ... See more keywords
Vacuolar (H+ )-ATPase subunit c is essential for the survival and systemic RNA interference response in Locusta migratoria.
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DOI: 10.1002/ps.6774
Abstract: BACKGROUND Vacuolar (H+ )-ATPase (V-ATPase) is a multi-subunit enzyme that hydrolyzes ATP to transport protons across a cellular membrane, and it plays an important role in numerous biological processes, including in growth, development and immune… read more here.
Keywords: vacuolar atpase; locusta migratoria; rna interference; lmv atpase ... See more keywords