Reticulophagy mediated by the V-ATPase-ATG16L1-LC3C axis
Sign Up to like & getrecommendations! Published in 2024 at "Autophagy"
DOI: 10.1080/15548627.2024.2317116
Abstract: ABSTRACT The lysosomal degradation of the endoplasmic reticulum (ER), known as “reticulophagy”, is important for protein quality control and organelle turnover. Here we present a noncanonical reticulophagy occurring at ER exit sites (ERESs) induced by… read more here.
Keywords: atpase atg16l1; mediated atpase; reticulophagy; lc3c ... See more keywords
Control of infection by LC3-associated phagocytosis, CASM, and detection of raised vacuolar pH by the V-ATPase-ATG16L1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn3298
Abstract: The delivery of pathogens to lysosomes for degradation provides an important defense against infection. Degradation is enhanced when LC3 is conjugated to endosomes and phagosomes containing pathogens to facilitate fusion with lysosomes. In phagocytic cells,… read more here.
Keywords: lc3 associated; associated phagocytosis; atpase atg16l1; atpase ... See more keywords