Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine
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DOI: 10.1038/s41467-021-23854-x
Abstract: The hexameric AAA-ATPase Drg1 is a key factor in eukaryotic ribosome biogenesis and initiates cytoplasmic maturation of the large ribosomal subunit by releasing the shuttling maturation factor Rlp24. Drg1 monomers contain two AAA-domains (D1 and… read more here.
Keywords: structural basis; inhibition; atpase drg1; drg1 ... See more keywords