Cardiac glycosides stimulate endocytosis of GLUT1 via intracellular Na+,K+‐ATPase α3‐isoform in human cancer cells
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DOI: 10.1002/jcp.30762
Abstract: Glucose transporter GLUT1 plays a primary role in the glucose metabolism of cancer cells. Here, we found that cardiac glycosides (CGs) such as ouabain, oleandrin, and digoxin, which are Na+,K+‐ATPase inhibitors, decreased the GLUT1 expression… read more here.
Keywords: cancer; atpase isoform; glut1; human cancer ... See more keywords