Targeting ferroptosis contributes to ATPR-induced AML differentiation via ROS-autophagy-lysosomal pathway.
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DOI: 10.1016/j.gene.2020.144889
Abstract: Ferroptosis, a newly discovered form of non-apoptotic cell death, is induced by an excessive degree of iron-dependent lipid peroxide. ATPR, a novel all-trans retinoic acid (ATRA) derivative, has been extensively developed to show superior anticancer… read more here.
Keywords: ferroptosis; differentiation; ferroptosis contributes; contributes atpr ... See more keywords