Preclinical evaluation of SC0245, a small molecule inhibitor of ATR kinase.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e15642
Abstract: e15642Background: The ataxia telangiectasia and Rad3-related (ATR) kinase is a member of the phosphoinositide 3-kinase related kinase (PIKK) family. ATR plays an important role in maintaining genom... read more here.
Keywords: preclinical evaluation; kinase; small molecule; atr kinase ... See more keywords
Benzothiazole and Chromone Derivatives as Potential ATR Kinase Inhibitors and Anticancer Agents
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27144637
Abstract: Despite extensive studies and the great variety of existing anticancer agents, cancer treatment remains an aggravating and challenging problem. Therefore, the development of novel anticancer drugs with a better therapeutic profile and fewer side effects… read more here.
Keywords: compound; chromone derivatives; benzothiazole chromone; kinase ... See more keywords