ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment.
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DOI: 10.1016/j.celrep.2017.02.040
Abstract: Melanomas accumulate a high burden of mutations that could potentially generate neoantigens, yet somehow suppress the immune response to facilitate continued growth. In this study, we identify a subset of human melanomas that have loss-of-function… read more here.
Keywords: melanoma; mutations promote; atr mutations; immune microenvironment ... See more keywords