Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo
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DOI: 10.1158/1078-0432.ccr-18-0628
Abstract: Purpose: The catalytic function of BUB1 is required for chromosome arm resolution and positioning of the chromosomal passenger complex for resolution of spindle attachment errors and plays only a minor role in spindle assembly checkpoint… read more here.
Keywords: parp inhibitors; bay 1816032; atr parp; bub1 kinase ... See more keywords