Reevaluation of ATR signaling in primary resting chronic lymphocytic leukemia cells: evidence for pro-survival or pro-apoptotic function
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DOI: 10.18632/oncotarget.18144
Abstract: ATM, primarily activated by DNA double-strand breaks, and ATR, activated by single-stranded DNA, are master regulators of the cellular response to DNA damage. In primary chronic lymphocytic leukemia (CLL) cells, ATR signaling is considered to… read more here.
Keywords: chronic lymphocytic; atr signaling; pro apoptotic; cll cells ... See more keywords
The Autonomous Parvovirus Minute Virus of Mice Localizes to Cellular Sites of DNA Damage Using ATR Signaling
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DOI: 10.3390/v15061243
Abstract: Minute Virus of Mice (MVM) is an autonomous parvovirus of the Parvoviridae family that replicates in mouse cells and transformed human cells. MVM genomes localize to cellular sites of DNA damage with the help of… read more here.
Keywords: virus mice; damage; dna damage; minute virus ... See more keywords
Phosphoproteomics of ATR signaling in mouse testes
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DOI: 10.7554/elife.68648
Abstract: The phosphatidylinositol 3′ kinase (PI3K)‐related kinase ATR is crucial for mammalian meiosis. ATR promotes meiotic progression by coordinating key events in DNA repair, meiotic sex chromosome inactivation (MSCI), and checkpoint-dependent quality control during meiotic prophase… read more here.
Keywords: atr; mouse testes; signaling mouse; atr signaling ... See more keywords