Articles with "atrasentan" as a keyword



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Organic Anion Transporter Gene Variants Associated With Plasma Exposure and Longā€Term Response to Atrasentan in Patients With Diabetic Kidney Disease

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Published in 2022 at "Clinical Pharmacology and Therapeutics"

DOI: 10.1002/cpt.2721

Abstract: Plasma exposure of the endothelin receptor antagonist atrasentan varies between individuals and is associated with nephroprotective effects and the risk of heart failure. We examined the influence of genetic polymorphisms on atrasentan plasma exposure and… read more here.

Keywords: atrasentan; kidney; plasma exposure; transporter ... See more keywords