Elevated potassium outward currents in hyperoxia treated atrial cardiomyocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26263
Abstract: Supplementation of 100% oxygen is a very common intervention in intensive care units (ICU) and critical care centers for patients with dysfunctional lung and lung disorders. Although there is advantage in delivering sufficient levels of… read more here.
Keywords: treated atrial; atrial cardiomyocytes; hyperoxia; outward currents ... See more keywords
Identification of an endogenous glutamatergic transmitter system controlling excitability and conductivity of atrial cardiomyocytes
Sign Up to like & getrecommendations! Published in 2021 at "Cell Research"
DOI: 10.1038/s41422-021-00499-5
Abstract: As an excitatory transmitter system, the glutamatergic transmitter system controls excitability and conductivity of neurons. Since both cardiomyocytes and neurons are excitable cells, we hypothesized that cardiomyocytes may also be regulated by a similar system.… read more here.
Keywords: transmitter system; glutamatergic transmitter; system; atrial cardiomyocytes ... See more keywords
PITX2c impairment electrical remodeling increases susceptibility to atrial fibrillation
Sign Up to like & getrecommendations! Published in 2023 at "Europace"
DOI: 10.1093/europace/euad122.583
Abstract: Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): the National Research Foundation of Korea (NRF) grants funded by the Korea government (MSIT), the Korean Fund for Regenerative… read more here.
Keywords: atrial cardiomyocytes; electrical remodeling; pitx2c; pitx2 ... See more keywords
Nr2f1a maintains atrial nkx2.5 expression to repress pacemaker identity within venous atrial cardiomyocytes of zebrafish
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DOI: 10.1101/2022.02.24.481762
Abstract: Maintenance of cardiomyocyte identity is vital for normal heart development and function. However, our understanding of cardiomyocyte plasticity remains incomplete. Here, we show that sustained expression of the zebrafish transcription factor (TF) Nr2f1a prevents the… read more here.
Keywords: nkx2 expression; atrial cardiomyocytes; identity; expression ... See more keywords
SAR296968, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Ca2+ Handling and Contractile Function in Human Atrial Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10081932
Abstract: Background: In reverse-mode, cardiac sodium-calcium exchanger (NCX) can increase the cytoplasmic Ca2+ concentration in response to high intracellular Na+ levels, which may contribute to diastolic contractile dysfunction. Furthermore, increased spontaneous Ca2+ release from intracellular stores… read more here.
Keywords: function; novel selective; atrial cardiomyocytes; inhibitor ... See more keywords
Transcriptomic Profile of Genes Regulating the Structural Organization of Porcine Atrial Cardiomyocytes during Primary In Vitro Culture
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DOI: 10.3390/genes13071205
Abstract: Numerous cardiovascular diseases (CVD) eventually lead to severe myocardial dysfunction, which is the most common cause of death worldwide. A better understanding of underlying molecular mechanisms of cardiovascular pathologies seems to be crucial to develop… read more here.
Keywords: culture; atrial cardiomyocytes; transcriptomic profile; vitro culture ... See more keywords