Mechanism underlying the contractile activity of UTP in the mammalian heart
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.04.013
Abstract: Abstract We previously reported that uridine 5’‐triphosphate (UTP), a pyrimidine nucleoside triphosphate produced a concentration‐ and time‐dependent increase in the contraction force in isolated right atrial preparations from patients undergoing cardiac bypass surgery due to… read more here.
Keywords: effect utp; heart; effect; atrial preparations ... See more keywords
Cardiovascular effects of metoclopramide and domperidone on human 5-HT4-serotonin-receptors in transgenic mice and in human atrial preparations.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174074
Abstract: It is unclear whether metoclopramide and domperidone act on human cardiac serotonin 5-HT4-receptors. Therefore, we studied transgenic mice that only express the human 5-HT4 receptor in cardiomyocytes in the atrium and in the ventricle (5-HT4-TG),… read more here.
Keywords: ht4; transgenic mice; human ht4; metoclopramide domperidone ... See more keywords