Phase I Study of the Anti-HtrA1 Antibody-Binding Fragment FHTR2163 in Geographic Atrophy Secondary to Age-Related Macular Degeneration.
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DOI: 10.1016/j.ajo.2021.06.017
Abstract: PURPOSE FHTR2163 is a novel antigen-binding fragment (Fab) directed against high-temperature requirement protein A1 (HtrA1). HtrA1 inhibition may preserve retinal integrity and slow disease progression in geographic atrophy (GA) secondary to age-related macular degeneration (AMD).… read more here.
Keywords: secondary age; age; atrophy secondary; study ... See more keywords