Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2023.2097
Abstract: Importance The global prevalence of myopia is predicted to approach 50% by 2050, increasing the risk of visual impairment later in life. No pharmacologic therapy is approved for treating childhood myopia progression. Objective To assess… read more here.
Keywords: dose atropine; myopia progression; progression; trial ... See more keywords
The effect of sublingual atropine sulfate on clozapine-induced hypersalivation: a multicentre, randomised placebo-controlled trial.
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05627-4
Abstract: BACKGROUND Hypersalivation and drooling are commonly reported in clozapine-treated patients. Current management strategies have been evaluated using subjective measures. Many case reports describe the successful use of atropine in the treatment of the condition. AIMS… read more here.
Keywords: sublingual atropine; clozapine; hypersalivation; effect ... See more keywords
Studies on retinal mechanisms possibly related to myopia inhibition by atropine in the chicken
Sign Up to like & getrecommendations! Published in 2019 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-019-04573-y
Abstract: Purpose While low-dose atropine eye drops are currently widely used to inhibit myopia development in children, the underlying mechanisms are poorly understood. Therefore, we studied possible retinal mechanisms and receptors that are potentially involved in… read more here.
Keywords: retinal mechanisms; myopia; myopia inhibition; atropine ... See more keywords
Short-Term Effects of Atropine 0.01% on the Structure and Vasculature of the Choroid and Retina in Myopic Chinese Children
Sign Up to like & getrecommendations! Published in 2022 at "Ophthalmology and Therapy"
DOI: 10.1007/s40123-022-00476-0
Abstract: To explore the short-term effects of atropine 0.01% on the structure and vasculature of the choroid and retina in myopic Chinese children. This study was a single-center randomized clinical trial. A total of 40 subjects… read more here.
Keywords: effects atropine; group; short term; atropine structure ... See more keywords
Atropine for the Prevention of Myopia Progression in Children: A Report by the American Academy of Ophthalmology.
Sign Up to like & getrecommendations! Published in 2017 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2017.05.032
Abstract: PURPOSE To review the published literature on the efficacy of topical atropine for the prevention of myopic progression in children. METHODS Literature searches were last conducted in December 2016 in the PubMed database with no… read more here.
Keywords: progression children; ophthalmology; myopic progression; atropine ... See more keywords
Comment on: ‘Cochrane corner: Atropine: an ancient remedy for a twenty-first century problem?’
Sign Up to like & getrecommendations! Published in 2020 at "Eye"
DOI: 10.1038/s41433-020-01165-7
Abstract: We read with interest the recent Comment on atropine in Eye [1]. Unfortunately, the casual reader may be misled by a number of incomplete statements. First, the authors state that atropine showed “an estimated 1.00… read more here.
Keywords: comment; myopia; authors state; treatment ... See more keywords
Selective recognition of atropine in biological fluids and leaves of Datura stramonium employing a carbon nanotube–chitosan film based biosensor
Sign Up to like & getrecommendations! Published in 2018 at "New Journal of Chemistry"
DOI: 10.1039/c8nj01312h
Abstract: This paper demonstrates a selective, expeditious and facile electrochemical approach for the ultrasensitive detection of atropine in complex matrices. Herein, a non-destroyable composite of surface decorating single walled carbon nanotubes on a biopolymer chitosan film… read more here.
Keywords: carbon; biosensor; chitosan film; atropine ... See more keywords
Low Dose Atropine in Preventing the Progression of Childhood Myopia: A Randomised Controlled Trial
Sign Up to like & getrecommendations! Published in 2022 at "Current Eye Research"
DOI: 10.1080/02713683.2022.2162925
Abstract: Abstract Purpose To study the efficacy of low dose atropine (0.01%) eye drops in preventing myopia progression in children by comparing the mean change in spherical equivalent (diopter) and axial length (mm) over a period… read more here.
Keywords: change; near vision; group; atropine ... See more keywords
Symptoms and ocular findings associated with administration of 0.01% atropine in young adults
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Optometry"
DOI: 10.1080/08164622.2022.2033603
Abstract: ABSTRACT Clinical relevance This paper provides eye care practitioners with important information about the potential side effects of 0.01% atropine. Background Eye care practitioners routinely administer 0.01% atropine eye drops nightly to slow the progression… read more here.
Keywords: administration; administration atropine; side effects; eye ... See more keywords
Atropine Ophthalmic Solution to Reduce Myopia Progression in Pediatric Subjects: The Randomized, Double-Blind Multicenter Phase II APPLE Study.
Sign Up to like & getrecommendations! Published in 2023 at "Asia-Pacific journal of ophthalmology"
DOI: 10.1097/apo.0000000000000609
Abstract: PURPOSE The purpose of this study was to assess the dose-response effects of low-dose atropine on myopia progression and safety in pediatric subjects with mild-to-moderate myopia. METHODS This phase II, randomized, double-masked, placebo-controlled study compared… read more here.
Keywords: myopia progression; randomized double; atropine; pediatric subjects ... See more keywords
The penetration and distribution of topical atropine in animal ocular tissues
Sign Up to like & getrecommendations! Published in 2019 at "Acta Ophthalmologica"
DOI: 10.1111/aos.13889
Abstract: To conduct a multi‐tissue investigation on the penetration and distribution of topical atropine in myopia treatment, and determine if atropine is detectable in the untreated contralateral eye after uniocular instillation. read more here.
Keywords: distribution topical; topical atropine; penetration distribution; atropine ... See more keywords