Carbene-Catalyzed Atroposelective Annulation and Desymmetrization of Urazoles.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01191
Abstract: An NHC-catalyzed atroposelective reaction between ynals and urazoles is disclosed. The reaction establishes a chiral C-N axis via an atroposelective [3 + 2] annulation/desymmetrization process. Our reaction allows efficient access to axially chiral and heteroatom-rich… read more here.
Keywords: annulation desymmetrization; carbene catalyzed; atroposelective annulation; catalyzed atroposelective ... See more keywords
Carbene-Catalyzed Atroposelective Annulation for Quick Access to Axially Chiral Thiazine Derivatives
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28104052
Abstract: An N-heterocyclic carbene (NHC)-catalyzed atroposelective annulation reaction is disclosed for quick and efficient access to thiazine derivatives. A series of axially chiral thiazine derivatives bearing various substituents and substitution patterns were produced in moderate to… read more here.
Keywords: atroposelective annulation; thiazine derivatives; chiral thiazine; thiazine ... See more keywords