Catalytic Atroposelective Friedel-Crafts Alkylation to Access Axially Chiral C2-Arylindoles via Dynamic Kinetic Resolutions
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DOI: 10.1039/d4qo01611d
Abstract: Indole-based atropisomers have emerged as an important backbone in drug discovery and novel catalyst/ligand design. However, the development of asymmetric synthesis of axially chiral 2-arylindoles is sluggish due to the... read more here.
Keywords: friedel crafts; axially chiral; atroposelective friedel; crafts alkylation ... See more keywords